Although bacterial ('z') factors are thought to be quite different from the specificity factors employed in higher organisms, a comparison of the ('z')/RNA polymerase structures with recent structures of eukaryotic Pol II together with TFIIB highlights significant functional similarities
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Transcription Regulation at the Core: Similarities Among Bacterial, Archaeal, and Eukaryotic RNA Polymerases

Annual Review of Microbiology

Review in Advance first posted online on June 13, 2013. (Changes may still occur before final publication online print.)

DOI: 10.1146/annurev-micro-092412-155756

 Kimberly B. Decker

Unit on Microbial Pathogenesis, Cell Biology and Metabolism Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892

 Deborah M. Hinton

Gene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892; email: dhinton@helix.nih.gov

http://www.annualreviews.org/doi/abs/10.1146/...412-155756