Glioblastoma, an aggressive brain cancer, and Alzheimer's disease share some similarities, including:

Brain tissue
Brain tissue from glioblastoma patients can show signs of Alzheimer's disease, such as beta-amyloid, amyloid precursor protein, and tau.

Accelerated aging
The brain of glioblastoma patients can show accelerated aging, similar to Alzheimer's disease.

Gene expression
Glioblastoma and Alzheimer's disease share similar patterns of gene expression, and both diseases upregulate the immune system.

Cellular behavior
Alzheimer's disease is characterized by increased cell death, while cancer is characterized by excessive cell growth. However, both diseases share a pathway in gene transcription.