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Posted On: 10/20/2024 1:51:39 PM
Post# of 148863
“The neurons in his right hemisphere were shut down due to the stroke.”
Like most things in medicine it is more nuanced…there is first a qualitative difference between stroke from occlusion and hemorrhagic stroke and there are pivotal differences in treatment that hang on that distinction. Patients get a stat CT for that reason as you don’t want to be giving alteplase if it is hemorrhagic…if it is obstructive they can clot bust but these days they can actually capture and retrieve the clot through a catheter in some cases… patients have been known to actually walk out of the hospital the same day. There are coronal areas around the stroke area that are taking a hit…those neurons could roll over and die but might be salvaged with good perfusion and adjunctive treatment, which I suspect includes Leronlimab which works against the inflammation and that inflammation in turn can be problematic with regard to perfusion. I know of a physician looking to do an investigator initiated study of nitric oxide (which will cause vasodilation and encourage re- perfusion in the umbral area affected by stroke)…to a great extent it’s about giving damaged neurons the best shot at recovery.
Like most things in medicine it is more nuanced…there is first a qualitative difference between stroke from occlusion and hemorrhagic stroke and there are pivotal differences in treatment that hang on that distinction. Patients get a stat CT for that reason as you don’t want to be giving alteplase if it is hemorrhagic…if it is obstructive they can clot bust but these days they can actually capture and retrieve the clot through a catheter in some cases… patients have been known to actually walk out of the hospital the same day. There are coronal areas around the stroke area that are taking a hit…those neurons could roll over and die but might be salvaged with good perfusion and adjunctive treatment, which I suspect includes Leronlimab which works against the inflammation and that inflammation in turn can be problematic with regard to perfusion. I know of a physician looking to do an investigator initiated study of nitric oxide (which will cause vasodilation and encourage re- perfusion in the umbral area affected by stroke)…to a great extent it’s about giving damaged neurons the best shot at recovery.
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