The claim for Plexin-b1 seems to be in the area of a reduction in Amyloid plaque...and there is still questions about Amyloid plaque being an effective gateway... to a reduction in Alzheimers activity.

Alzheimers disease is a fire...CCR5 wrapping of Macrophage with Large Molecule is an effective way of smothering fire to exhaustion...well at least that's ...how I see it.