“Chronic inflammation has been implicated in the pathophysiology of various psychiatric disorders, including depression and schizophrenia.”

Interesting thesis by AI but I agree with OHM20, there is a lot we don’t know and the current state of research suggests we are not sitting on the kind of compelling data as exists even for CCR5 and cancer. That said I had a fascinating conversation with a psychiatrist on New Year’s Eve and he was reflecting on the fact that there is heightened focus on neuro-inflammatory underpinnings to some of the psychiatric conditions in his wheelhouse. The physician I spoke with when the topic came up suggested one theory on why ECT might be working for severe depression is that it does trigger a fairly profound inflammatory response but does lead to kind of a reset below whatever resting inflammatory state might have been there pre-ECT.