"Itching in PBC"...ohm...I love that there is no capitilization in your nom de plume...it shows that in spite of your knowledge... you are still in a state of humility...stay there.

IF and I say IF...a drug performs above a placebo effect (which varies) ...how is the placebo effect supposed baseline determined against actual results... I am at a loss...

As a lay person...If I am given a product and told you will feel better...and I do...that's success...
IF it lasts for twenty-four hours and I relapse...that's failure in my eyes. ARE We on the right path or wandering into the wilderness?