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Posted On: 01/12/2022 1:15:58 PM
Post# of 148900
Re: onestepahead #114822
Nice article. Agree that Omicron infection is not just mild disease, but something like 99% of people will have mild disease, many more than before.
I always wondered about this. What are the factors determining who will develop long hauler's disease, and what will be the other long term implications of Covid infection (e.g. von Economo's encephalitis / parkinsonism post Spanish Flu)? Is severity of disease related to long hauler's? Age? vaccination status? and most importantly, I was wondering if use of leronlimab in mild, moderate, severe, and critical disease would lower the risk of long hauler's disease. If somehow using leronlimab was able to reset the immune system, so to speak, and keep it from getting so out of whack to cause long hauler's symptoms.
Then again, there are still many ideas on what causes long haul Covid, whether it be autoimmune, persistent inflammatory response, persistent infection of classical monocytes and associated endothelial dysfunction, other viral reservoir somewhere else, or other. Of course the long term effects of vaccination are also unknown, so one takes ones chances either way. But it's best probably not to be infected. Hard to believe everyone won't eventually though.
Quote:
Van Kerkhove warned people should not become fatalistic and resign themselves to infection, cautioning that the long-term health implications of catching omicron remain unknown.
I always wondered about this. What are the factors determining who will develop long hauler's disease, and what will be the other long term implications of Covid infection (e.g. von Economo's encephalitis / parkinsonism post Spanish Flu)? Is severity of disease related to long hauler's? Age? vaccination status? and most importantly, I was wondering if use of leronlimab in mild, moderate, severe, and critical disease would lower the risk of long hauler's disease. If somehow using leronlimab was able to reset the immune system, so to speak, and keep it from getting so out of whack to cause long hauler's symptoms.
Then again, there are still many ideas on what causes long haul Covid, whether it be autoimmune, persistent inflammatory response, persistent infection of classical monocytes and associated endothelial dysfunction, other viral reservoir somewhere else, or other. Of course the long term effects of vaccination are also unknown, so one takes ones chances either way. But it's best probably not to be infected. Hard to believe everyone won't eventually though.
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