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I believe this is why the avidtadil effects were more evident in days 28-60 than 0-28, and arguably why the DSMB apparently saw a sign of additional placebo mortality in days 28-42.

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To add to this, I believe its possible that Aviptadil may show results if given enough time. From what we know about Leronlimab from our EIND results, the improvement from LL begins rapidly. Most seeing improvement within 3 days, all within 14 days.

For this reason, I think its pretty likely that if the data is analyzed from days 28-42, we will see the mortality heavily weighted toward placebo.