I’ve looked at lenzilumab much more closely. I think this is overlooked pretty often. It is a fascinating drug but I’ve spoken to a few clinician and most of them have said it has a very gray area on when to administer. Give it too early and you suppress the immune system completely.

Leronlimab is much safer and to your second part, yes there are more mechanism of action taking place other than GM-CSF.

I’m sure someone like OHM can give an answer in greater detail.