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Posted On: 11/22/2020 5:03:48 PM
Post# of 149015
Can you explain to a layman such as myself the progression in steps 5 and 6?
I’m particularly interested and confused by the following from step 6. How/why does CCL5 “decrease drug cytotoxic activity?”
TIA. Perhaps I need to look up “cytotoxic activity.” Is this the same as toxic side effects of drugs entering the body?
Quote;
“(6) CCL5 secreted by tumor cells and by the TME decreases drug cytotoxic activity. “
I’m particularly interested and confused by the following from step 6. How/why does CCL5 “decrease drug cytotoxic activity?”
TIA. Perhaps I need to look up “cytotoxic activity.” Is this the same as toxic side effects of drugs entering the body?
Quote;
“(6) CCL5 secreted by tumor cells and by the TME decreases drug cytotoxic activity. “
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