"A lot will also depend on price... outside the US, prophylaxis may be too costly/it may make more sense to treat only those 15% that progress to Severe/Critical."

I'm confused. Are you referring to Leronlimab here or to the Pfizer vaccine to treat Severe/Critical. I have limited medical knowledge but thought that a vaccine would not be helpful for patients already sick with Covid since their immune systems will already have been stimulated plenty enough to produce antibodies. Please clarify.