In the severe/critical trial, with 37 leronlimab patients and 14 placebo patients, if one leronlimab patient died then at least two placebo patients would have to die to achieve p<0.5.

See website below

Probability of success on a single trial: 12/14=0.85714

Number of trials = 37

Number of successes = 36

Binomial probability = 0.0256

Not sure if I am doing the problem correctly but I think so

https://stattrek.com/online-calculator/binomial.aspx