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I am unclear about the potential for an interim analysis on the mild/moderate trial, but I would think there would be a mechanism for it. Perhaps someone else recalls that.

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I certainly hope it might be possible, but like you, my optimism is extremely guarded. The other issue, if I am not mistaken, is the the Mild-Moderate trial would have to progress to a P3 -- which would conceivable take even more time to enroll and conduct.