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Innovation Pharmaceuticals IPIX
(Total Views: 361)
Posted On: 03/24/2020 10:06:18 AM
Post# of 72446
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Posted By: Drano
New data analysis: chloroquine doesn't work very well if at all. The Chinese study involved only 30 patients, so to get actual conclusive results there needs to be a bigger clinical trial. It doesn't look good on the basis of this study.

Quote:
a key analyst has found trial data that contradict the conclusions from a small positive Chinese study that researchers initially based on their enthusiasm on.
....
The main goal of the study — virological clearance rate — was higher on the placebo arm at 93%, versus 87% on the hydroxychloroquine cohort. Temperature normalization was essentially the same — 1 day in both groups. Radiological progression on CT images favored hydroxychloroquine — 33% on the drug arm, compared to 47% in the control group — but these data are hard to interpret since there were just 5 versus 7 cases that progressed, Raffat cautioned.

“It really puzzles me why we’re seeing inaccurate characterizations of clinical data…having an honest discussion around emerging clinical data would actually help the progress,” he said.

“For instance, were the patients in this dosed early enough in this trial? (No disclosure on that). Also, were the baseline viral loads balanced across arms? Parsing through emerging data for these important drivers of success can help define what an effective treatment window and optimal candidate looks like.”


https://endpts.com/wall-street-analyst-finds-...-patients/

Looks to me like it's worth a try if someone is at risk of death -- but tragically it's not going to be the magic wonder drug we hoped for.















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