And BTW , doing now density tests for every patients for pivotal , and dose patients 525 or 700 depending on the results should not be done now
( except if required by FDA )
, it is much more risky since we have no experience how accurate this test is now .. Very new test , not proven for some time and many patients as it should be for such an important study ,,

I will do 700 mg to all patients , approve the medicine , even unofficially do the tests to see how well it is correlating ...

And tune up the treatment later ...

Of course all IMO only...