(Total Views: 151)
Posted On: 03/05/2019 5:21:51 PM
Post# of 154736
Trding, thank you for looking into this....I wasn't meaning to give you a project to dig into....you already research plenty.
Not having a science background, I just thought it interesting (on the surface anyway) that the "cure" was linked to CCR5...and like you pointed out the individual had indications of GvHD, HIV and cancer....and leronlimab appears to work well with all of these.
It was also interesting to me about the CCR5-negative comment: "bone marrow transplantation from a CCR5-negative donor can eliminate residual virus and stop any traces of virus from rebounding"...."Two factors are likely at play: The new bone marrow is resistant to HIV, and also, the new bone marrow is actively eliminating any HIV-infected cells."
Maybe several years down the road we will find that combining leronlimab with some CRISPR editing will provide cures?
Not having a science background, I just thought it interesting (on the surface anyway) that the "cure" was linked to CCR5...and like you pointed out the individual had indications of GvHD, HIV and cancer....and leronlimab appears to work well with all of these.
It was also interesting to me about the CCR5-negative comment: "bone marrow transplantation from a CCR5-negative donor can eliminate residual virus and stop any traces of virus from rebounding"...."Two factors are likely at play: The new bone marrow is resistant to HIV, and also, the new bone marrow is actively eliminating any HIV-infected cells."
Maybe several years down the road we will find that combining leronlimab with some CRISPR editing will provide cures?
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