P53 is a universal protector - so even if aberrant p53, a gene mutation of p53 called mutant p53, is not causing a specific cancer, then Kevetrins purported ability to preserve and enhance cancer fighting expression of healthy wild-type p53, which is involved in all cancers, in all cells - make it number one on the list. Aberrant p53 is mutant p53 and we know its a huge cancer causer. NF Kappa B is also huge, huge drug opportunity area because it is involved in many inflammatory conditions and cancers, and the company that develops molecule optimizing its protective expression will also be sitting on one of the biggest drugs ever. Like p53, NF Kappa B has universal cellular protective properties and when it mutates and those protections are lost, cancers grow, immune system inhibition occurs, viruses wrap themselves in lookalike and go undetected. And fwiw, p53 has been shown to induce activation of nf kappa B. So - kevetrin could be a drug version of a 10 course meal...