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Posted On: 05/30/2017 3:54:19 PM
Post# of 72446

Re: someconcerns #34319
The Keytruda news has great implication on Kevetrin. P53 is a gene and mutant p53 contains mutations in the nucleic acid sequence. So I think mutant p53 should qualify as a genetic marker. Kevetrin has the ability to degrade mutant p53 and hopefully the K-OC trial will confirm its MOA.
Quote:
Merck & Co's immunotherapy Keytruda on Tuesday became the first cancer drug ever approved by the U.S. Food and Drug Administration based on a patients' specific genetic traits, regardless of where in the body the disease originated.


