Getting the right dosage could be the tricky part, just look at P2a & P2b of B-ABSSSI. I do agree that safety is not going to be a problem. The highest dosage (200 mg) of P is still less than Ziagen (300 mg).

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It's possible a higher dose is needed relative to the mice, for efficacy. Or it's possible that the dose can be lower. Or it's possible that it doesn't work at any dose.

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