I don't think it was brought up yesterday or not on the board but Fumi posted about a possible link to MANF? Check it out but I believe it's referencing MANF in the blog, which is great as it is getting so much exposure and research attention...

Quote:

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My former trainee who is currently a staff scientist at UCSF and I gave lectures in the same session at a scientific meeting. I gave a lecture on Wolfram syndrome, and my former trainee, Rajarshi Ghosh, described a new small molecule that can be used for the treatment of ER stress-related diseases, including diabetes and retinitis pigmentosa . I was very proud of Rajarshi and his accomplishments. I was so happy.

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http://wolframsyndrome.blogspot.ca/2014/08/th...l?spref=tw