Immuron Partners With Monash to Combat Antimicrobial Resistance

Collaborative Efforts Against Antimicrobial Resistance

Highlights:

• New Research Collaboration with Monash University
• Focus on Developing Therapeutics to Combat Pathways Related to Antimicrobial Resistance
• Projects Aiming to Create Drug Candidates Targeting Vancomycin-resistant Enterococci (VRE)

Immuron Limited (ASX: IMC; NASDAQ: IMRN), a globally integrated biopharmaceutical company based in Australia, is excited to share its new research agreement with Monash University. This partnership aims to tackle the pressing issue of antimicrobial resistance (AMR), a challenge impacting healthcare systems worldwide.

The primary goal of this collaboration is to develop innovative therapeutic options focusing on antimicrobial-resistant pathogens. By leveraging Immuron's proprietary technology and the expertise of Monash’s Biomedicine Discovery Institute, specifically under the leadership of Professor Dena Lyras, the teams are poised to make significant advancements in this field.

This collaboration marks the beginning of a journey aimed at understanding and combating mechanisms contributing to AMR. And importantly, Immuron will utilize its existing research funding to support initial activities, ensuring that no additional financial resources are necessary at this stage.

With a detailed research plan in place, the parties involved will engage in good faith negotiations regarding the potential for joint development or commercialization of successful outcome discoveries, further emphasizing the collaborative spirit of this initiative.

The First Project Proposal: Understanding Bacterial DNA Transfer

The first project will delve into the mechanisms through which bacteria exchange DNA, an essential process that can quickly modify bacterial traits, leading to the rise of antimicrobial resistance. The ultimate objective is to devise broad-spectrum therapeutic agents capable of countering resistant bacterial strains.

AMR represents a critical threat to global healthcare, causing infections that are not only harder to treat but also result in extended hospital stays, increased medical costs, and elevated mortality rates. In fact, recent estimates suggest that treating such infections costs the U.S. healthcare system upwards of $4.6 billion each year. As the fight against AMR intensifies, the need for effective solutions becomes increasingly urgent.

Targeting Vancomycin-resistant Enterococci (VRE)

The second significant focus of this collaboration will specifically address Vancomycin-resistant enterococci (VRE). VRE bacteria, as their name implies, exhibit resistance to vancomycin, complicating treatment in various healthcare environments. These pathogens have surfaced as major issues within hospitals and other healthcare facilities, especially among vulnerable populations like the elderly and those with weakened immune systems.

The most notable strains of VRE, including Enterococcus faecalis and Enterococcus faecium, contribute to a range of hospital-acquired infections. The consequences of VRE infections can lead to severe health complications, increased risk of subsequent infections, and unfortunately, potential mortality for the affected individuals. This highlights the need for new therapeutic strategies to combat these formidable pathogens.

The Rising Need for Innovative Therapeutics

According to industry forecasts, the global market for antibiotics may reach approximately $57.0 billion by 2026, growing at a compound annual growth rate of 4.0%. This growth is largely attributed to the increasing occurrence of drug-resistant infections. The urgent demand for novel treatments in this critical arena drives research endeavors like that of Immuron and Monash University.

This collaboration not only reflects a timely response to a major public health crisis but also demonstrates a commitment to addressing the rising tide of antimicrobial resistance. By focusing on developing comprehensive solutions, Immuron and its partners are taking significant steps toward enhancing healthcare outcomes for patients worldwide.

About Immuron Limited

Immuron Limited is an Australian biopharmaceutical company dedicated to developing and commercializing orally administered targeted polyclonal antibodies tailored for the treatment of infectious diseases. Their commitment to innovative solutions underlines their approach toward addressing complex health challenges.

Contact Information

COMPANY CONTACT:
Steven Lydeamore
Chief Executive Officer
steve@immuron.com

Frequently Asked Questions

What is the main focus of the collaboration between Immuron and Monash University?

The collaboration primarily targets developing therapeutic candidates to address antimicrobial resistance, particularly focusing on pathways related to VRE.

Why is antimicrobial resistance a significant concern globally?

AMR poses a severe threat to healthcare systems by making infections more difficult to treat, which can lead to increased healthcare costs and higher mortality rates.

What are Vancomycin-resistant enterococci?

VRE are a group of bacteria that have developed resistance to the antibiotic vancomycin, complicating treatment options for patients in healthcare settings.

How is Immuron contributing to this research area?

Immuron is leveraging its technology platform and existing research budget to support studies aimed at understanding and addressing antimicrobial resistance through the development of new therapies.

What market trends are influencing antibiotic development?

The global demand for innovative antibiotics is increasing, with the market projected to reach $57.0 billion by 2026, primarily due to the rise of drug-resistant infections.

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