Kineta's KVA12123 to Be Showcased at Major Cancer Conference

Kineta's KVA12123 Presentation Highlights at SITC 2024

Kineta, Inc., a clinical-stage biotech firm operating in the world's most promising area of oncology, recently shared exciting news. They announced that their abstract for the KVA12123 clinical program has garnered acceptance for a poster presentation at the Society for Immunotherapy of Cancer (SITC) 40th Annual Meeting. This prestigious event is set to take place in early November, bringing together some of the brightest minds in cancer research.

Key Presentation Details

During the conference, specifically on November 8, Jason Henry, M.D., specializing in Drug Development, will present findings from an ongoing Phase 1/2 clinical trial of KVA12123. This innovative therapy, designed to block VISTA (V-domain Ig suppressor of T cell activation), is being evaluated both as a standalone treatment and alongside Merck's renowned anti-PD-1 treatment, KEYTRUDA, in patients battling advanced solid tumors.

Title and Authors of the Study

The presentation is titled "A phase 1/2 clinical trial of anti-VISTA – KVA12123 alone and in combination with pembrolizumab in patients with advanced solid tumors." This research includes contributions from a diverse set of experts in the field, enhancing the depth and credibility of the findings presented.

Event Logistics and Importance

The scheduled session will showcase abstract number 625 during the conference proceedings, where participants can engage with cutting-edge insights on cancer therapies. This development signifies a notable moment for Kineta, especially given their focus on transitioning innovative research into applicable treatments for cancer patients.

About Kineta's Revolutionary Approach

Kineta's commitment to creating next-generation immunotherapies is evidenced in their robust approach to addressing challenges faced in current cancer treatments. With KVA12123 in a Phase 1/2 trial, it aims to tackle immune resistance which significantly hampers treatment efficacy. The ongoing studies are particularly notable, as they explore the combination of KVA12123 with well-known therapies, potentially enhancing treatment options for many patients.

Insights on KVA12123

KVA12123 has shown considerable potential for tumor growth inhibition in preclinical trials, not only as a monotherapy but also in conjunction with other immune checkpoint inhibitors. As a promising immunotherapy, it targets tumors that exhibit immune suppression, aiming to create a more favorable tumor microenvironment for patient T cells to effectively combat cancer.

Recent Corporate Moves and Future Directions

In an effort to streamline operations and reduce expenditures, Kineta underwent significant corporate restructuring earlier in the year. This included workforce adjustments and the strategic halt of new patient enrollments in ongoing trials. Such moves are intended to strengthen the company's position as they explore avenues to maximize value for stockholders, including potential partnerships and opportunities in their business model.

Forward-Looking Statements and Investor Relations

While exciting developments abound, potential investors and stakeholders are encouraged to regard forward-looking statements with caution when considering Kineta's plans and strategies regarding KVA12123 and other product candidates. Kineta emphasizes its commitment to transparency, urging stakeholders to remain informed about risks and uncertainties associated with clinical advancements.

Frequently Asked Questions

What is the focus of Kineta, Inc.?

Kineta, Inc. focuses on developing novel immunotherapies for cancer, particularly those that address immune resistance.

What is KVA12123?

KVA12123 is a VISTA-blocking immunotherapy currently involved in clinical trials to assess its efficacy in treating advanced solid tumors.

When will Kineta present their findings?

Kineta will present findings at the SITC 40th Annual Meeting on November 8, with a focus on the KVA12123 trial results.

What is the significance of the SITC conference?

The SITC conference is a prominent event in the oncology field, showcasing research and innovations in cancer immunotherapy to global audiences.

How can I learn more about Kineta and their therapies?

To learn more about Kineta and their ongoing research, you can visit their official website.

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