Innovative Vaccine Trial for Long COVID By Hyundai Bioscience

Investigative Trial Launches to Tackle Long COVID

Hyundai Bioscience has taken a significant step in addressing Long COVID by partnering with the University of California San Diego (UCSD) for an investigator-initiated trial. This collaboration aims to evaluate the efficacy of Xafty, a novel antiviral derived from niclosamide, developed by Hyundai's Korean headquarters. The trial will be spearheaded by Dr. Ajay Bharti, a clinical trialist with a deep expertise in infectious diseases and the neurocognitive effects of viral infections.

Understanding the Challenge of Long COVID

Long COVID continues to affect millions globally, manifesting in various debilitating symptoms such as chronic fatigue, inflammation, and cognitive decline. Current treatment options are limited and typically address singular aspects of this multifaceted condition. Dr. Davey Smith, Director of UCSD's Altman Clinical and Translational Research Institute, emphasizes the urgency in finding effective therapies for this syndrome, which has no reliable treatment available today.

The Promise of Xafty

Xafty stands out as a promising oral antiviral that enhances the bioavailability of niclosamide, which has demonstrated antiviral properties against over 30 viruses. Currently undergoing a phase 3 clinical trial in Korea targeting high-risk populations, Xafty reportedly improves symptom resolution quicker than existing treatments. The drug is also anticipated to apply for phase 3 trials with the U.S. FDA in the near future, underlining its potential impact in the fight against COVID-19 and its related long-term effects.

Innovative Mechanism to Address Symptoms

Addressing the unique complexities of Long COVID, Xafty may provide solutions beyond mere viral suppression. Instead, it aims to inhibit inflammation and protect nerve cells. The active ingredient, niclosamide, could potentially facilitate recovery across multiple fronts. Unlike conventional treatments that target one aspect of the illness, the multifaceted approach of Xafty could revolutionize current therapeutic strategies.

Recent Research Breakthroughs

Recent studies conducted by Hyundai Bioscience provided compelling evidence for Xafty’s neuroprotective qualities. In research on Parkinson's disease, animals treated with Xafty exhibited increased dopamine production and improved nerve cell recovery compared to those receiving standard care. This meaningful finding suggests that Xafty could significantly address cognitive issues such as brain fog, a common symptom among Long COVID patients.

Expectations for Non-Traditional Treatment

Dr. Ajay Bharti conveyed his enthusiasm about utilizing Xafty to combat Long COVID. After observing promising results in COVID-19 trials, he is optimistic that Xafty's success in neuroprotection could lead to tangible improvements in the quality of life for patients experiencing complex symptoms of Long COVID. The compelling data from its prior trials reinforces the hope for effective solutions.

The Future of Long COVID Treatments

Hyundai Bioscience believes that confirming Xafty's capability to address the multifaceted symptoms of Long COVID could be groundbreaking. If successful, the clinical trial would not only pave the way for a viable treatment option but also set historical precedent in understanding and managing Long COVID. Looking forward, they aim to provide comprehensive therapeutic solutions that embrace the intricate nature of this syndrome.

About Hyundai Bioscience

Founded in 2000, Hyundai Bioscience specializes in drug development using advanced delivery systems designed to effectively deliver therapeutic agents. The company focuses on repurposing current drugs to expand their indications and improve health outcomes for various ailments. Publicly traded on KOSDAQ under the symbol 048410, Hyundai Bioscience is committed to innovation in biotechnology and improving global health.

Frequently Asked Questions

What is the main goal of the trial involving Xafty?

The primary aim is to evaluate the efficacy of Xafty in treating Long COVID symptoms, focusing on its ability to address complex conditions associated with this syndrome.

Who is leading the investigative trial for Xafty?

Dr. Ajay Bharti, an infectious disease specialist, leads the trial at UCSD, leveraging his expertise in clinical trials and viral illnesses.

How does Xafty differ from existing treatments for Long COVID?

Xafty's approach involves a multi-mechanistic strategy, addressing inflammation and neuroprotection alongside viral suppression, which is often lacking in traditional treatments.

What previous studies support the use of Xafty?

Research conducted on Parkinson's disease indicated that Xafty could enhance dopamine production and nerve recovery, which may be beneficial for Long COVID patients.

What is Hyundai Bioscience's focus in drug development?

Hyundai Bioscience focuses on creating innovative drug delivery systems to enhance the therapeutic effects of existing medications, aimed at improving patient health outcomes.

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