Immutep Showcases Promising Efti Data for Soft Tissue Sarcoma
Exciting Updates from Immutep on Efti in Soft Tissue Sarcoma
Immutep Limited (ASX: IMM; NASDAQ: IMMP) is making significant strides in oncology with its innovative approach to treating soft tissue sarcoma. New data from the EFTISARC-NEO Phase II trial has surfaced, demonstrating the potential of a novel triple combination therapy involving efti, radiotherapy, and KEYTRUDA®, paving the way for better treatment outcomes in this challenging field.
Presentation of Groundbreaking Findings
Upcoming details reveal that these results will be presented at the highly regarded Connective Tissue Oncology Society 2024 Annual Meeting. This event is set to take place in November, showcasing the efforts of expert researchers in the field, and further confirming the importance of this research.
Background on EFTISARC-NEO
The EFTISARC-NEO trial stands out as it is the very first to assess efti in a neoadjuvant setting. This allows clinicians to access tumor tissue before and after treatment, thus providing valuable insights into efti's influence on the tumor microenvironment. Initial efficacy data presented in early 2024 was incredibly promising, with most patients showing deep responses not commonly observed in soft tissue sarcoma cases treated with standard therapies.
The Urgency of Addressing Soft Tissue Sarcoma Needs
Soft tissue sarcoma (STS) represents a significant medical challenge, classified as an orphan disease characterized by poor prognosis and a compelling need for effective treatments. The annual incidence of STS varies across Europe, with approximately 23,400 new cases reported according to recent studies. In the United States, projections for 2024 estimate about 13,590 new STS cases, leading to roughly 5,200 deaths, highlighting the urgent demand for more effective therapeutic options.
Moving Forward with the EFTISARC-NEO Study
The open-label EFTISARC-NEO study aims to include up to 40 patients and is being conducted in collaboration with the prominent Maria Sk?odowska-Curie National Research Institute of Oncology in Warsaw. Funding for this trial is primarily sourced from a grant approved by the relevant Polish authorities, underscoring the commitment to advancing research in this critical area.
The Future of Efti and Patient Care
Post the presentation at CTOS 2024, Immutep intends to make the findings accessible by announcing them on the ASX and providing the poster presentation in the Posters & Publications section of its official website. This step reflects Immutep's dedication to transparency and knowledge dissemination within the medical community.
About Immutep and Its Vision
Immutep is at the forefront of immunotherapy development through its innovative LAG-3 products targeting cancer and autoimmune diseases. The company harnesses its deep understanding of LAG-3 to produce therapies that can modulate the immune system effectively. Their goal is to ensure that breakthrough treatments reach those in dire need, whilst maximizing shareholder value. To learn more, visit their website.
Frequently Asked Questions
What is the main focus of the EFTISARC-NEO trial?
The EFTISARC-NEO trial evaluates the efficacy of a triple combination therapy of efti, radiotherapy, and KEYTRUDA® in treating soft tissue sarcoma.
Where will the results of the EFTISARC-NEO trial be presented?
Results will be presented at the Connective Tissue Oncology Society 2024 Annual Meeting in November.
Why is soft tissue sarcoma considered an orphan disease?
Soft tissue sarcoma is classified as an orphan disease due to its rarity, significant medical need, and poor patient prognosis.
How many patients will be involved in the EFTISARC-NEO study?
The study aims to enroll up to 40 patients, focusing on the effectiveness of the new treatment combination.
What does Immutep specialize in?
Immutep specializes in developing novel LAG-3 immunotherapies for oncology and autoimmune diseases, striving to provide innovative treatment solutions.
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