Huadong Medicine and SynerK Collaborate on Innovative siRNA Therapy

Exciting Partnership between Huadong Medicine and SynerK

Huadong Medicine Co., Ltd., known for its commitment to innovative healthcare solutions, has partnered with SynerK PharmaTech to develop a groundbreaking small interfering RNA (siRNA) drug named SNK-2726. This novel medication is designed specifically to tackle hypertension by targeting angiotensinogen (AGT), a critical component in managing blood pressure levels.

Significance of the Innovative siRNA Drug SNK-2726

SNK-2726 represents a significant advancement in RNA-targeted therapies. This medication is currently in the Investigational New Drug (IND) application preparation stage, indicating that it is progressing through essential regulatory pathways to ensure its efficacy and safety. The joint efforts of Huadong Medicine and SynerK will leverage their combined strengths to expedite the development of SNK-2726.

Potential Benefits for Hypertensive Patients

The mechanism of action for SNK-2726 rests on its ability to inhibit the production of AGT in the liver. By reducing AGT levels, the drug disrupts the renin-angiotensin-aldosterone system (RAAS), known for significantly influencing blood pressure regulation. The result could be sustained blood pressure control, which is vital for the millions affected by hypertension.

Strategic Cooperation and Expected Outcomes

In the strategic cooperation agreement, Huadong Medicine obtains an exclusive option, allowing them to develop, register, manufacture, and commercialize SNK-2726 for the Greater China market. This collaboration not only underscores Huadong Medicine's robust infrastructure in the pharmaceutical industry but also highlights SynerK's innovative technologies.

A Vision for Patient-Centric Outcomes

Both companies are determined to make a meaningful impact on patient health. Dr. Tao Lan, the CEO of SynerK, expressed excitement regarding the collaboration, emphasizing shared goals for patient-centered outcomes. Likewise, Lv Liang, the Chairman of Huadong Medicine, confirmed the commitment to accelerate the developmental timeline for SNK-2726, ensuring that effective treatment options reach patients swiftly.

About the Characteristics of SNK-2726

SNK-2726 boasts a unique design as a subcutaneous RNA interference drug that specifically targets AGT. The preclinical studies indicate its efficacy in significantly lowering AGT and, consequently, blood pressure. Such findings position SNK-2726 as a promising candidate in the hypertension treatment landscape, which is often challenged by the limitations of existing therapies.

Who is SynerK?

SynerK is dedicated to pioneering RNA-targeted therapeutic advancements. Based in both the USA and China, SynerK was co-founded by seasoned experts in nucleic acid therapies. Their mission focuses on developing first-in-class medications for challenging diseases that are inadequately addressed by current treatment options.

Huadong Medicine’s Commitment to Innovation

Established in 1993, Huadong Medicine Co., Ltd. embraces a full-spectrum operational model within the pharmaceutical industry. Its corporate philosophy is deeply rooted in scientific research and a focus on patient needs. The company has expanded its offerings across various segments, reflecting a comprehensive approach to pharmaceutical care.

A Successful Track Record

Over three decades, Huadong Medicine has evolved into a key player in the pharmaceutical industry, evidenced by its substantial operational revenue and dedicated workforce. With more than 10,000 employees, the company is well-equipped to handle extensive commercial endeavors, ensuring that innovative therapies like SNK-2726 can be efficiently brought to market.

Frequently Asked Questions

What is the purpose of the drug SNK-2726?

SNK-2726 is designed to treat hypertension by targeting and inhibiting angiotensinogen (AGT), which plays a crucial role in blood pressure regulation.

Who is developing SNK-2726?

SNK-2726 is being developed through a strategic cooperation between Huadong Medicine and SynerK PharmaTech.

What stage is SNK-2726 currently in?

SNK-2726 is currently at the IND application preparation stage, moving through regulatory processes necessary for drug approval.

How does SNK-2726 work?

It effectively inhibits the production of AGT, thereby blocking the RAAS system's activity and reducing blood pressure over time.

What is Huadong Medicine's focus in the pharmaceutical industry?

Huadong Medicine focuses on comprehensive pharmaceutical research, development, production, and distribution, aiming to innovate patient-centered treatments.

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