Henlius Unveils Innovative Strategies at 2025 R&D Day Event

Henlius 2025 Global R&D Day: A Focus on Innovation
Henlius (2696.HK) recently hosted its 2025 Global R&D Day, themed "Collaborate to Create." This significant event brought together senior executives, experts, and industry leaders to delve into the latest R&D advancements, strategic planning, and innovative therapies. The gathering attracted hundreds, highlighting the synergy between academia, industry, and investment sectors.
Innovative Therapies and Developments
During the event, Henlius presented its impressive pipeline of innovative therapies, which includes serplulimab, an anti-PD-1 monoclonal antibody, HLX22, an anti-HER2 monoclonal antibody, and HLX43, a PD-L1 antibody-drug conjugate (ADC). These therapies are designed to meet the urgent needs in addressing lung and gastrointestinal cancers. Significantly, HLX43 stands out as China's first and the world's second PD-L1 ADC, effectively combining a proprietary antibody with MediLink's advanced dual-release payload, showcasing promising preclinical efficacy and favorable safety profiles.
Henlius' Technological Advancements
In addition to its groundbreaking therapies, Henlius highlighted three key innovative technology platforms. The Hinova TCE platform focuses on tri-specific T-cell engagers for solid tumors, while the proprietary Hanjugator™ ADC platform and the AI-driven drug discovery platform HAI Club have established a collaborative matrix conducive to developing differentiated therapies. Furthermore, Henlius is making strides in the strategic development of its innovative hyaluronidase, Henozye™, and advancing subcutaneous injection technologies to enhance drug formulations and biosimilars, while also prolonging product lifecycles.
Global Strategy and Market Expansion
As globalization remains a primary focus, Japan has been identified as a strategic market within Henlius' "Internationalization 2.0" strategy. The company is taking advantage of Japan's aging population and its favorable regulatory environment to propel clinical trials for both HLX22 and serplulimab, striving for a seamless integration of R&D and commercialization. During the "Partnering for Success" panel, 2022 Nobel Laureate Prof. Carolyn Bertozzi spoke about the potential of sialoglycan-targeting therapies in oncology and immunology. Henlius' collaboration has accelerated the development of the human sialidase fusion protein HLX79 (E-602).
Building Partnerships for Success
Industry leaders emphasized Henlius' strong capabilities in antibody development, clinical execution, and global-quality manufacturing as crucial drivers for establishing impactful alliances. The company is dedicated to expanding its therapeutic ecosystem worldwide through partnerships grounded in trust and collaboration.
Future Directions: Patient-Centric Innovations
The event concluded with an emphatic call for industry-wide collaboration aimed at bridging the gap between preclinical and clinical stages. The emphasis on leveraging AI together with data-driven strategies is crucial for accelerating patient-centric innovation. By 2025, Henlius is committed to transforming technological advancements into tangible clinical benefits, solidifying China's growing presence in the global biopharmaceutical arena.
Frequently Asked Questions
What was the main theme of Henlius' 2025 R&D Day?
The main theme was "Collaborate to Create," focusing on enhancing innovation and strategic planning.
What key therapies were showcased by Henlius?
Henlius showcased serplulimab, HLX22, and HLX43, targeting various cancers.
How is Henlius advancing its technology?
Henlius is utilizing innovative platforms like Hinova TCE, Hanjugator™, and HAI Club for enhanced therapy development.
Which market is a focus for Henlius under its globalization strategy?
Japan is prioritized as a strategic market in Henlius' "Internationalization 2.0" strategy.
What are Henlius’ goals for the future?
Henlius aims to turn technological advancements into clinical value and reinforce its global impact.
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