HELP Therapeutics and China Resources Sanjiu Team Up for Heart Health
Strategic Partnership for Advanced Heart Failure Treatment
HELP Therapeutics, recognized as a pioneer in regenerative medicine, has entered into a strategic partnership with China Resources Sanjiu Pharmaceutical Company, one of China’s foremost pharmaceutical firms. This collaboration focuses on the co-development and commercialization of HiCM-188, an innovative investigational cell therapy designed specifically for advanced heart failure.
Addressing a Growing Health Crisis
Heart failure continues to be a significant health concern globally, and its incidence is rising dramatically. In one region alone, approximately 12 million adults are affected by this serious condition, with nearly three million new cases emerging annually. The survival rates over five years for heart failure patients are alarmingly low, similar to rates seen in many aggressive cancers. While heart transplantation offers a potential lifeline, less than one in a thousand patients find a suitable donor in time, highlighting the urgent need for alternative treatments. This is where advancements in cell therapy, like HiCM-188, hold great promise for changing patient care.
Significant Milestones with HiCM-188
HiCM-188 stands out as the first iPSC-derived regenerative therapy for heart failure that has received IND clearance in both China and the United States. Currently, this promising candidate is undergoing Phase II clinical trials in China and Phase I/II trials across various regions including the U.S. and Southeast Asia. Its long-term safety and efficacy have been validated through data collected over more than five years, providing a strong foundation for its use in clinical practice.
Expert Insights on the Partnership
Dr. Wang Jiaxian, the Founder and CEO of HELP Therapeutics, regards this partnership as a pivotal moment. "Joining forces with China Resources Sanjiu unlocks significant opportunities to enhance our therapy's reach and effectiveness," he stated. His perspective underscores the importance of their clinical expertise and innovative approach to accelerating solutions for patients in need.
Expanding Horizons in Cell Therapy
Mr. Qiu Huawei, Chairman of China Resources Sanjiu, reflected on the company’s commitment to the future of life sciences, especially in the realm of cell therapy. By leveraging resources from their subsidiary, Tasly Pharmaceuticals, they aim to foster innovation in this crucial area. "Our collaboration with HELP Therapeutics enables us to combine our strengths, paving the way for groundbreaking advancements in treating refractory conditions like heart failure," he added.
A Transformative Collaboration in Research
Professor Junbo Ge from the Chinese Academy of Sciences has recognized this partnership as a historical development within China’s Cell and Gene Therapy landscape. He shared that HELP Therapeutics’ strategic focus on addressing heart failure aligns with urgent clinical needs and the necessity for targeted myocardial repair solutions. "This partnership has the potential to dramatically shift treatment paradigms on a global scale," he remarked.
About HELP Therapeutics
HELP Therapeutics is at the forefront of regenerative medicine, specializing in the development of groundbreaking treatments for heart failure and other critical health conditions. With their innovative iPSC platform and extensive clinical pipeline, they are committed to reshaping patient care through state-of-the-art cell therapies.
Frequently Asked Questions
What is the focus of the partnership between HELP Therapeutics and China Resources Sanjiu?
The partnership aims to co-develop and commercialize HiCM-188, a cell therapy designed to treat advanced heart failure.
Why is heart failure a significant health concern?
Heart failure is increasing in prevalence and is associated with low survival rates. Alternatives to heart transplantation are urgently needed due to the limitation of suitable donor hearts.
What stages of clinical trials is HiCM-188 currently in?
HiCM-188 is undergoing Phase II trials in China and Phase I/II trials in the United States and other regions.
How does HiCM-188 differ from other heart failure treatments?
HiCM-188 is the first iPSC-derived therapy approved in both China and the U.S., offering a potential alternative to traditional treatments.
What role does HELP Therapeutics play in the regenerative medicine field?
HELP Therapeutics specializes in developing innovative therapies, particularly focused on heart failure, using advanced cell technology.
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