Grant Approval for Innovative Glioblastoma Treatment at RFU
NIH Fast-Track Grant for Glioblastoma Treatment
U.P. Oncolytics, a trailblazer within the Rosalind Franklin University Helix 51 incubator, has garnered an NIH fast-track grant aimed at developing a groundbreaking treatment for glioblastoma, a notoriously aggressive and often deadly form of brain cancer.
Significant Funding to Propel Research Forward
The grant provides $500,000 for the first year of the company's Phase I-Phase II SBIR Fast-Track initiatives, designed to facilitate promising scientific projects that display strong potential for commercialization. U.P. Oncolytics' research will focus on validating a novel approach employing oncolytic Zika virus for glioblastoma treatment.
The Urgence of Glioblastoma
Glioblastoma remains one of the most challenging cancers to treat, accounting for over 50% of all malignant brain tumors. Unfortunately, around 10,000 individuals in the U.S. succumbed to glioblastoma in the past year alone. The median survival rate for this condition is merely eight months, with a five-year survival rate standing at a daunting 6.9%.
Innovative Approach to a Daunting Challenge
Richard Rovin, MD, a co-founder of U.P. Oncolytics and an experienced neurosurgeon, emphasizes the urgency and significance of advancing treatment options for glioblastoma. According to Rovin, the last two decades have witnessed a stark lack of substantial progress in treatment methodologies for this devastating illness.
What Sets This Treatment Apart?
Dr. Parvez Akhtar, co-founder and Chief Scientific Officer, highlights the initial findings that suggest the Zika virus might effectively overcome glioblastoma's notorious resistance, including barriers such as the blood-brain barrier. The upcoming studies are geared towards validating these promising results and progressing towards filing an Investigational New Drug (IND) application with the FDA, ultimately leading to clinical trials.
Community Support and Vision for the Future
The executive leadership at Rosalind Franklin University, represented by Dr. Ronald Kaplan, expresses great optimism regarding U.P. Oncolytics' innovative research endeavors. The hope is that breakthroughs in glioblastoma treatment will significantly improve patient outcomes and survivorship.
About Rosalind Franklin University
Rosalind Franklin University of Medicine and Science serves as an incubator for innovation, nurturing various health-related research initiatives.
About U.P. Oncolytics
U.P. Oncolytics is committed to developing cutting-edge therapies and is spearheading efforts to bring effective glioblastoma treatments to market.
Frequently Asked Questions
What is the purpose of the NIH Fast-Track grant?
The NIH Fast-Track grant aims to provide funding for scientifically promising projects that show high potential for commercial success.
How much funding has U.P. Oncolytics received?
U.P. Oncolytics has received a $500,000 grant for the first year of their project.
What is glioblastoma?
Glioblastoma is the most common and aggressive form of brain cancer, with very low survival rates and a high rate of progression.
How does the Zika virus relate to glioblastoma treatment?
Research indicates that the Zika virus may be effective in overcoming glioblastoma's resistance mechanisms, potentially leading to more successful treatments.
What are the next steps for U.P. Oncolytics?
The next steps include validating their initial findings through additional studies and moving towards an FDA Investigational New Drug application.
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