Exploring Advanced Oncology Solutions at Altogen Labs
Innovative Approaches to Oncology at Altogen Labs
Altogen Labs is a leading preclinical research organization dedicated to advancing the field of oncology through its innovative testing and evaluation of new treatments. With a focus on pharmacological and biological therapies, the company aims to bring novel anticancer medications, vaccines, and natural products to the forefront of medical science. The dedicated team at Altogen Labs employs cutting-edge technologies to ensure that their research leads to meaningful progress in cancer treatment and drug development.
Comprehensive Oncology Services Offered
The laboratory offers a wide range of specialized immuno-oncology services, incorporating advanced humanized and immunodeficient rodent models. These models include those engrafted with peripheral blood mononuclear cells (PBMC), CD34+ hematopoietic stem cells, and induced pluripotent stem cells (iPSC). This robust platform allows Altogen Labs to evaluate immune responses as well as assess drug efficacy and potential toxicity, thereby providing valuable insights into the therapeutic potential of new cancer treatments.
Xenograft Models for Drug Discovery
One of the significant strengths of Altogen Labs is their extensive collection of over 100 in-house validated xenograft models. These models include conventional CDX, patient-derived xenografts (PDX), and in vitro approaches such as patient-derived cell cultures and organoids. This comprehensive array of models enables Altogen Labs to predict drug efficacy based on genetically characterized cancer models, ensuring that research aligns closely with clinical realities. This combination of testing methods, particularly in vivo assessments, is critical for generating reliable preclinical data.
Focus on Toxicity and Safety Studies
Ensuring the safety of potential drug candidates is paramount in Altogen Labs' research agenda. Their toxicity studies are conducted in three phases: acute, sub-chronic, and chronic studies. Acute studies evaluate short-term effects of compounds, while the other phases assess safety over extended periods. By thoroughly understanding potential adverse effects, the company aims to enhance the clinical efficacy and safety of the therapies they develop. The integration of various dosage levels and administration routes in in vivo efficacy and safety studies further optimizes drug delivery and biodistribution, crucial for investigational new drugs (INDs).
About Altogen Labs
Located in Austin, Texas, Altogen Labs specializes in providing preclinical and biological contract research organization (CRO) services for safety and efficacy studies. The company's mission revolves around supporting early-stage drug discovery and the development of innovative therapies. With a steadfast commitment to excellence and a team of skilled scientists, Altogen Labs has become a trusted partner for researchers in oncology and immunotherapy.
Contact Information
For those interested in collaborating or learning more about Altogen Labs, the company can be reached through their contact information provided on their platform. Their commitment to advancing research and therapeutic solutions positions them at the cutting edge of oncology research.
Frequently Asked Questions
What services does Altogen Labs provide?
Altogen Labs offers preclinical research services specializing in oncology, including immuno-oncology services and safety studies.
What types of models does Altogen Labs use?
The company utilizes advanced humanized and immunodeficient rodent models, including various xenograft models for drug testing.
How does Altogen Labs ensure the safety of drug candidates?
They conduct extensive toxicity studies, including acute, sub-chronic, and chronic evaluations to assess potential adverse effects.
What is the focus of Altogen Labs' research?
Altogen Labs concentrates on drug discovery and development in oncology, aimed at innovating cancer therapies.
Where is Altogen Labs located?
The research facility is based in Austin, Texas, and provides a range of preclinical CRO services.
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