Exciting Phase 2 Results of Evorpacept Presentation at ASCO

ALX Oncology's Promising Presentation of Evorpacept Results

ALX Oncology Holdings Inc. is generating excitement in the oncology community with the announcement of updated results from its Phase 2 ASPEN-06 clinical trial. This pivotal study highlights the potential of evorpacept, an innovative treatment designed to enhance the immune system's ability to combat cancer, specifically targeting HER2-positive gastric cancer. The results have been accepted for oral presentation at the prestigious American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium.

Details of the ASPEN-06 Clinical Trial

ASPEN-06 is a well-structured, multi-center trial that systematically evaluates the effectiveness of evorpacept in conjunction with other established treatments. This clinical trial focuses on patients suffering from HER2-positive gastric and gastroesophageal junction cancer, particularly those who have previously undergone anti-HER2 therapies.

What is Evorpacept?

Evorpacept is a groundbreaking investigational therapeutic developed by ALX Oncology. Uniquely, it combines a high-affinity CD47-targeting domain with an inactivated proprietary Fc domain, marking a significant advancement in targeting myeloid checkpoints in cancer therapy. In this trial, evorpacept is administered alongside trastuzumab and CYRAMZA® (ramucirumab) as well as paclitaxel, also known as TRP therapy.

Insights from the Upcoming Presentation

The oral presentation will feature a comprehensive analysis of the trial's outcomes, underlining the importance of evorpacept in redefining treatment protocols for HER2-positive gastric cancer. The presentation, to be directed by Dr. Kohei Shitara, a notable expert in the field, is set for January 23, 2025. This session is expected to draw significant interest as it could influence treatment approaches and patient outcomes in this challenging disease area.

Presentation Specifics

Dr. Shitara will present the final analysis of this randomized Phase 2 part of the ASPEN-06 study during the Rapid Oral Abstract Session A. Attendees can expect an insightful discussion on how evorpacept interacts with established therapies, potentially leading to improved patient care in the face of aggressive cancer types.

What’s Next for ALX Oncology?

As ALX Oncology continues to advance its clinical trials, the company remains dedicated to the mission of enhancing cancer care through innovative therapies. Evorpacept's promising results reflect ALX Oncology's commitment to improving the overall prognosis for patients with difficult-to-treat cancers. The company actively explores various cancer indications to refine therapeutic strategies and improve patient outcomes.

Keeping Stakeholders Informed

Following the oral presentation at ASCO, ALX Oncology will make detailed copies of the presentation available in the Publications section of its official website. This transparency is designed to keep healthcare professionals and investors informed about the latest advancements and findings from the company's clinical trials.

About ALX Oncology

ALX Oncology (NASDAQ: ALXO) is making strides as a clinical-stage biotechnology firm focused on developing therapies that harness the immune system against cancerous cells. Its flagship product, evorpacept, stands out as a potential key player in the immuno-oncology landscape. Clear evidence of its therapeutic possibilities rests on the ongoing clinical trials aimed at various cancer types. As the company progresses, they are eager to share updates and findings that could significantly impact cancer care and patients' lives.

Frequently Asked Questions

What is the ASPEN-06 clinical trial about?

The ASPEN-06 trial investigates the efficacy of evorpacept combined with other therapies for treating HER2-positive gastric cancer.

When will the results from the trial be presented?

The results will be presented on January 23, 2025, at the ASCO Gastrointestinal Cancers Symposium.

Who is presenting the trial results?

Dr. Kohei Shitara, a leading expert in gastrointestinal oncology, will present the findings from the trial.

Why is evorpacept significant in cancer therapy?

Evorpacept represents a novel approach to targeting myeloid checkpoints, offering hope for improved treatment outcomes in patients with aggressive cancers.

Where can I find more information about ALX Oncology?

More information about ALX Oncology and its therapies can be found on their official website and LinkedIn page.

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