Exciting Findings on Solnerstotug to be Revealed at ESMO Congress

Insightful Presentation on Solnerstotug
Boston-based Sensei Biotherapeutics, Inc. SNSE is establishing itself as a leader in the biopharmaceutical sector with innovative strategies targeting cancer treatment. The anticipated presentation of clinical data stemming from the Phase 1/2 trial at the upcoming ESMO Congress has everyone intrigued, especially with the spotlight on their promising product, Solnerstotug.
Clinical Data Highlights
In a mini oral session scheduled for October 17-21, the company plans to delve into the results from a Phase 1 expansion cohort of Solnerstotug—a pioneering anti-VISTA antibody, particularly when paired with the PD-1 inhibitor cemiplimab. This synergy could provide groundbreaking insights into treating patients who have shown resistance to prior PD-(L)1 therapy.
Details of the Upcoming Presentation
Dr. Kyriakos Papadopoulos, Co-Director of Clinical Research at START in San Antonio, will lead the presentation. Key details include:
- Title: Results from a Phase 1 expansion cohort of Solnerstotug combined with cemiplimab in advanced solid tumors.
- Abstract Number: 3933
- Time: Friday, October 17 from 2:00 – 3:30 CEST.
About Sensei Biotherapeutics
Sensei Biotherapeutics focuses on the creation and advancement of next-generation therapeutics, aiming to tackle the complexities of cancer treatment. Their innovative TMAb™ (Tumor Microenvironment Activated biologics) platform enables the design of therapeutics that selectively activate beneficial immune responses right where they are needed most—in the tumor microenvironment.
Solnerstotug is engineered to target the VISTA checkpoint selectively, which acts as a suppressor of T cells, thus potentially reversing resistance mechanisms employed by tumors.
Noteworthy Contact Information
For media inquiries, please contact:
Joyce Allaire
LifeSci Advisors
Jallaire@lifesciadvisors.com
Looking Ahead
The upcoming ESMO Congress serves as an important milestone for Sensei Biotherapeutics. By sharing these significant clinical findings, the company reinforces its commitment to advancing cancer care, potentially reshaping treatment protocols for many patients facing treatment-resistant tumors. With their advanced scientific expertise and dedication, Sensei is positioning itself at the forefront of cancer therapeutics.
Frequently Asked Questions
What is Solnerstotug?
Solnerstotug is a conditionally active antibody targeting the VISTA checkpoint in cancer treatment, designed to enhance T cell activation within the tumor microenvironment.
When will the clinical data be presented?
The clinical data from the Phase 1 expansion cohort will be revealed on October 17, during a mini oral session at ESMO Congress.
Who is presenting the data?
The presentation will be led by Dr. Kyriakos Papadopoulos, Co-Director of Clinical Research at START in San Antonio.
What does the TMAb™ platform do?
The TMAb™ platform allows the development of biologics that can selectively activate immune responses in the tumor microenvironment, combating immunosuppressive signals.
How is Sensei Biotherapeutics contributing to cancer treatment?
By focusing on innovative therapies like Solnerstotug and utilizing advancements in immuno-oncology, Sensei is advancing the fight against cancer.
About The Author
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