Excellos Partners with Galapagos for Innovative CAR-T Therapy
Excellos Joins Forces with Galapagos for CAR-T Therapy
Excellos Inc, a recognized contract development and manufacturing organization (CDMO), has announced its selection to produce CAR-T cell therapy candidate, GLPG5101, for Galapagos. This collaboration focuses on supporting a clinical study involving patients with relapsed or refractory non-Hodgkin lymphoma. The manufacturing operations will commence at Excellos' cutting-edge facility situated in downtown San Diego.
Galapagos' Decentralized Manufacturing Advantage
Galapagos, a clinical stage biotechnology company focused on innovative therapeutic solutions, aims to address critical medical needs globally. They utilize a decentralized manufacturing model that enhances the production process of CAR-T cell therapies. This innovative approach offers notable advantages such as quicker turnaround times and an improved patient experience.
In their new partnership, Excellos will be pivotal in streamlining production, ensuring fresh and effective cell therapies reach patients without unnecessary delays. The system is designed to maintain a median vein-to-vein time of just seven days, underscoring the project's potential to revolutionize CAR-T cell delivery.
Elevating Cancer Treatment Accessibility
This newly formed partnership signifies the first site activation stemming from the strategic collaboration between Galapagos’ U.S. operations and the Blood Centers of America (BCA). Under this alliance, BCA's extensive network of blood centers will back the decentralized manufacturing of Galapagos’ CAR-T therapies, thus enhancing patient accessibility to cutting-edge treatments.
“Our commitment to establishing a robust decentralized cell therapy manufacturing network across cancer treatment centers emphasizes our determination to improve patient access to these potentially life-saving therapies,” stated Bill Block, President and CEO of BCA. By leveraging insights from this collaboration, BCA aims to integrate numerous sites into Galapagos’ network swiftly.
Excellos' Commitment to Quality and Efficiency
Backed by impressive technological capabilities, Excellos boasts proprietary methods for cell characterization and reduction of variability in clinical responses. This expertise is critical for increasing the likelihood of successful outcomes in clinical applications. They provide comprehensive services including donor recruitment, cell isolation, transduction, and GMP production scale-up, positioning them well to adapt to the evolving needs of cell therapy.
The Path Ahead for Galapagos and Excellos
As Excellos embarks on this partnership with Galapagos, the company is bolstering its reputation within the cell therapy landscape. This collaboration is not merely about operational excellence but also about ensuring patients have timely access to innovative treatments.
“We are excited about this opportunity to collaborate with Galapagos, as it allows us to leverage our state-of-the-art facility and our agile team capable of adjusting to the fast-paced demands of cell therapy,” remarked Thomas VanCott, CEO of Excellos. The coordinated efforts between these organizations are set to significantly impact the future of cell therapy, enhancing the efficiency and efficacy of treatments available to patients.
A Commitment to Collaborative Innovation
The focus remains on leveraging unique capabilities of both Excellos and Galapagos to drive transformative change within the sector. Their synergy promises not only to optimize production but also to pave the way for a future where advanced therapies are more accessible to patients in need.
Frequently Asked Questions
What is the main goal of the collaboration between Excellos and Galapagos?
The partnership aims to enhance the production and delivery of CAR-T cell therapies, improving patient access and treatment efficiency.
How does decentralized manufacturing benefit CAR-T therapy production?
Decentralized manufacturing allows for faster production timelines and better management of clinical responses, making therapies more accessible to patients.
What role does the Blood Centers of America play in this collaboration?
BCA facilitates the decentralized manufacturing process, enabling the delivery of CAR-T therapies closer to cancer treatment centers.
What services does Excellos provide for cell therapy development?
Excellos offers comprehensive cGMP services, including donor recruitment, cell isolation, and GMP production scale-up for cell therapies.
What impact will this collaboration have on patient outcomes?
The collaboration is expected to enhance patient outcomes by providing timely access to innovative therapies and improving overall treatment experiences.
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