Everads Innovative Technology Enhances Eye Treatment Safety and Efficacy

Groundbreaking Clinical Results from Everads Therapy

Everads Therapy, a pioneering clinical stage biotechnology company, has recently shared its first-in-human trial results concerning an innovative suprachoroidal delivery technology. The study effectively demonstrates the safety, feasibility, and tolerability of the Everads Injector for delivering medication directly to the back of the eye through the suprachoroidal space.

Positive Outcomes from Initial Patient Cohort

The trial was presented at the prestigious EURETINA Congress, showcasing promising findings from the first cohort of patients. This open-label study aimed to assess the injector's capability to administer a triamcinolone acetonide suspension targeting diabetic macular edema (DME). The data highlights the effectiveness and ease of using the Everads Injector while establishing its potential in an office-based clinical setting.

Insights from the Study's Principal Investigator

Dr. Yoreh Barak, the Head of Retina at Rambam Medical Center and the principal investigator of the study, commented on the results, underscoring the effectiveness and convenience of the Everads Injector in clinical practice. He noted that the ability for clinicians to administer treatment non-surgically is a significant advancement toward more effective and less invasive solutions for posterior segment eye diseases.

Moving Forward with Patient Recruitment

The preliminary results from this initial patient cohort received clearance from the health authorities, which is a crucial milestone in the trial process. Encouragingly, Everads Therapy is currently in the process of recruiting additional patients for the next cohort. Full trial results are anticipated to be disclosed at forthcoming medical congresses.

CEO Remarks on the Trial's Impact

Expressing enthusiasm about the clinical outcomes, Moshe Weinstein, CEO of Everads, highlighted the potential of these findings to serve as a robust foundation for future clinical trial applications. He remarked that this data not only solidifies the technology's validity but also supports their collaborations with license partners and internal programs aimed at developing groundbreaking treatments for retinal diseases.

Understanding Suprachoroidal Delivery Technology

The suprachoroidal delivery technology developed by Everads allows for safe, efficient in-office delivery of therapeutic agents to retinal and choroidal tissues. Distinguished by its rapid delivery capabilities, it enhances the distribution of therapies throughout the posterior pole of the eye. This method may revolutionize the treatment landscape for retinal disorders, leading to more rapid and effective patient outcomes.

The Promise of Future Developments

A plethora of research continues to demonstrate the effectiveness of Everads Therapy's innovative delivery system. Studies highlighted by Yoreh Barak and Eclov R have showcased the technology's ability to reach macular regions swiftly, a critical factor in successfully treating conditions affecting the retina. Through ongoing developments and research collaborations, Everads is positioned at the forefront of advancements in the field of retinal health.

About Everads Therapy

Everads Therapy is committed to enhancing treatments for retinal diseases with its unique suprachoroidal delivery platform. By tackling the challenges presented by traditional methodologies, Everads aims to improve the efficacy and safety of existing and potential drug therapies. The company is actively engaged in collaborative projects involving gene therapy, cell therapy, and small molecule formulations. Everads emerged from DALI Medical Devices, which specializes in injectable drug delivery technologies, and operates within RAD Biomed, a renowned biotech accelerator. The foundational technologies of Everads were established by Professor Ygal Rotenstreich, reflecting the pioneering spirit embedded in their approach.

Frequently Asked Questions

What is the main goal of Everads Therapy?

The main objective of Everads Therapy is to optimize treatments for retinal diseases through its advanced suprachoroidal delivery technology.

How does the Everads Injector work?

The Everads Injector non-surgically delivers drugs into the suprachoroidal space at the back of the eye, targeting specific retinal conditions effectively.

What types of conditions are being targeted in the trials?

The initial trials focus on treating diabetic macular edema (DME), a significant condition affecting vision.

Who is leading the investigation for the Everads study?

Dr. Yoreh Barak, Head of Retina at Rambam Medical Center, serves as the principal investigator for the study.

What are the next steps for Everads Therapy?

Everads Therapy is actively recruiting more patients for the next trial cohort, with full trial results expected to be presented soon.

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