Commit Biologics Secures New Investment to Advance BiCE™ Platform

Commit Biologics Secures Additional Seed Financing

Commit Biologics has announced a significant extension to its seed financing, raising €5.5 million from the new investor Korys. This latest contribution is part of a greater investment strategy that brings their total seed financing to an impressive €21.5 million, demonstrating strong backing from the investment community. Korys joins existing syndicate members including Novo Holdings and Bioqube Ventures. The funds raised will be solely dedicated to enhancing Commit's Bispecific Complement Engaging (BiCE™) platform and progressing towards drug candidate selection.

Development Plans for the BiCE™ Platform

The financing will expedite the development of the BiCE platform which utilizes single domain antibodies designed to engage with the complement protein C1q. This engagement is crucial as it activates and directs the complement system—an essential feature of the innate immune system known for its rapid response capabilities. By leveraging this innovative platform, Commit Biologics aims to fine-tune its approach to specifically targeting and eradicating tumor cells, along with cells implicated in autoimmune diseases.

Key Leadership in Action

To facilitate the upcoming phases of development, Chief Scientific Officer Mikkel Wandahl Pedersen has been appointed as the Interim CEO of Commit Biologics. Dr. Pedersen is well-regarded in the fields of immuno-oncology and autoimmune disease research, bringing over 20 years of relevant experience to the position. His previous roles include being the Chief Scientific Officer at Nykode Therapeutics and Symphogen. In his remarks, Dr. Pedersen emphasized the importance of this new funding, highlighting its pivotal role in extending Commit's operational runway into late 2026.

Board Expansion with Industry Expertise

In conjunction with the financing, Eva Van Overmeire, a Senior Investment Manager at Korys, has joined the Board of Directors at Commit. Her insights and background in investment strategies and biotech will prove valuable as the company navigates the complexities of drug development. As shared by Eva, the platform’s ability to robustly activate the complement system represents a unique opportunity to significantly improve the lives of patients affected by cancer and autoimmune disorders.

About Commit Biologics and Its Vision

Founded out of Aarhus University, Commit Biologics is at the forefront of medical innovation, focusing on leveraging the body's complement system for therapeutic benefits. The BiCE™ technology offers a novel way to empower conventional monoclonal antibodies, enhancing their efficacy in activating the complement system. Through a sophisticated combination of single domain antibodies that target C1q and other cellular targets, Commit aspires to develop treatments that can meet the needs of patients battling various diseases.

Understanding the Complement System

The complement system plays a critical role within the immune response by helping to identify and eliminate pathogens. However, it remains a largely underutilized aspect of therapeutic strategies. Traditional monoclonal antibodies often face limitations in effectively engaging C1q due to structural constraints, which can compromise their therapeutic potential. Commit Biologics is working diligently to overcome these challenges with its innovative technology, aiming to enhance the natural ability of the immune system to target and destroy harmful cells.

A Look at Korys

Korys, the investment arm of the Colruyt family, is dedicated to creating sustainable value across various sectors including health, consumer products, and energy transformation. With a notable portfolio spanning over €4 billion, Korys seeks to partner with forward-thinking companies like Commit Biologics to drive impactful changes within their respective industries. Their investment philosophy is deeply rooted in value-driven entrepreneurship, positioning them as strong allies in supporting innovative projects.

Frequently Asked Questions

What is Commit Biologics working on with the new funding?

Commit Biologics is focusing on advancing its Bispecific Complement Engaging (BiCE™) platform towards drug candidate selection with the new funding.

Who has joined the Board of Directors of Commit Biologics?

Eva Van Overmeire from Korys has joined Commit Biologics' Board of Directors.

What is the role of Mikkel Wandahl Pedersen in Commit Biologics?

Mikkel Wandahl Pedersen has been appointed as Interim CEO while also continuing his role as Chief Scientific Officer.

How does the BiCE™ platform work?

The BiCE™ platform uses single domain antibodies to target the complement protein C1q, enhancing the body's immune response against tumor and autoimmune disease cells.

What is the significance of the complement system?

The complement system is a crucial part of the immune system, targeting pathogens and aiding in their elimination, but it has been underutilized in therapies.

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