CollPlant Advances Innovative Dermal Filler toward Clinical Trials

CollPlant's Breakthrough in Aesthetic Medicine

CollPlant Biotechnologies, a trailblazer in regenerative and aesthetic medicine, is now progressing towards clinical trials based on encouraging findings from its non-clinical studies of a revolutionary photocurable dermal filler. This product embodies a significant leap forward in aesthetic procedures, merging aesthetic precision with the ability to regenerate tissue, all in one treatment. The filler is crafted using CollPlant's proprietary non-animal recombinant human collagen (rhCollagen), focusing on safe and effective results for patients.

Advancements in Dermal Fillers

The innovative formulation of CollPlant’s dermal filler combines hyaluronic acid with a modified version of rhCollagen, delivering not just immediate effects but long-lasting benefits. Practitioners can administer the filler as a viscoelastic gel via a fine needle, which enables precise sculpting of facial contours. Following administration, a proprietary illumination device activates the gel, transforming it into a semi-solid state. This transition ensures that the filler can withstand everyday stress while maintaining its shape.

Key Milestones Achieved

Yehiel Tal, the CEO of CollPlant, expressed the company's enthusiasm, stating, "Successfully completing our non-clinical program is a pivotal moment for CollPlant as we embark on the clinical development of our photocurable regenerative filler. Utilizing the remarkable properties of our rhCollagen technology, we plan to set a new standard in aesthetic care with a solution that achieves not only immediate results but also supports natural tissue integration for enduring outcomes. We are eager to take the next step towards the clinic, getting us closer to bringing a transformative product to physicians and their patients."

Comprehensive Non-Clinical Evaluations

CollPlant's non-clinical journey included a thorough range of safety and performance assessments such as a year-long, in vivo study to confirm the filler’s durability. Additionally, the company conducted biocompatibility evaluations that adhered to international standards. These collective findings provide a solid groundwork for the forthcoming clinical trials, reinforcing CollPlant’s commitment to quality and safety while scaling up and enhancing its manufacturing processes to prepare for the trials ahead.

Expanding Horizons with Strategic Partnerships

The company has expanded its strategic partnerships significantly, including a notable collaboration with Allergan, an AbbVie company, which holds a strong position in the global market for dermal fillers. This partnership opens pathways for widespread commercialization of their innovative dermal and soft tissue fillers, reinforcing CollPlant's presence in the aesthetic space.

About CollPlant

CollPlant is a leader in regenerative and aesthetic medicine, pioneering advancements in 3D bioprinting of tissues and organs as well as tissue repair. The products are built on the foundation of rhCollagen, generated through its unique plant-based genetic engineering technology. These innovative solutions are designed to cater to a variety of medical applications ranging from aesthetic enhancements to critical tissue repair.

Frequently Asked Questions

What is CollPlant's major recent announcement?

CollPlant announced encouraging results from its non-clinical studies for its photocurable dermal filler, transitioning towards clinical trials.

How does CollPlant's dermal filler work?

The filler is injected as a viscoelastic gel that activates into a semi-solid state under light, providing lasting structural support while contouring.

What role does rhCollagen play in CollPlant's products?

rhCollagen, derived from proprietary technology, is the main ingredient in CollPlant's products, enhancing safety and performance in regenerative solutions.

What are the next steps for CollPlant regarding this filler?

CollPlant aims to further advance the photocurable dermal filler into clinical trials, following successful non-clinical evaluations.

How does CollPlant ensure its products meet safety standards?

The company conducts extensive safety and performance evaluations, adhering to international compliance standards and conducting long-term durability studies.

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