Celebrating Innovations: CHOP Researchers Join AACR Academy 2025
Celebrated Researchers Elected to the AACR Academy
Garrett M. Brodeur and Stephan A. Grupp to be honored at AACR's Annual Meeting
Children's Hospital of Philadelphia (CHOP) proudly announces that two exceptional cancer researchers, Garrett M. Brodeur, MD, and Stephan A. Grupp, MD, PhD, have been selected for the prestigious 2025 class of the Fellows of the American Association for Cancer Research (AACR) Academy.
Impactful Contributions to Cancer Research
Each year, the AACR Academy recognizes remarkable scientists whose innovative work significantly advances the battle against cancer. This distinguished group represents a vital collective of experts in the fields of cancer advocacy, communication, and funding aimed at enhancing cancer research initiatives.
Dr. Brodeur, who heads CHOP's Cancer Predisposition Program and serves as a Professor of Pediatrics at the Perelman School of Medicine, is being acknowledged for his fundamental contributions to neuroblastoma research. His work includes identifying MYCN amplification as a key indicator of high-risk neuroblastoma and contributing to the development of an International Neuroblastoma Staging System. Additionally, he has pioneered the preclinical advancement of TRK inhibitors aimed at treating pediatric solid tumors and organized critical workshops focused on pediatric cancer predisposition and monitoring. His novel multivalent nanomedicine, PEEL-24, promises to offer a more effective and safer alternative to traditional therapies, such as irinotecan.
Revolutionizing Pediatric Cancer Treatments
Dr. Grupp, the Section Chief of Cellular Therapy and Transplant, and the inaugural Director of the Kelly Center for Cancer Immunotherapy at CHOP, is recognized for his groundbreaking research that led to the transformative chimeric antigen receptor T-cell (CAR T-cell) therapy. This innovation has reshaped personalized cancer treatment protocols, resulting in the FDA's approval of tisagenlecleucel, a significant milestone as the first CAR T-cell and gene therapy sanctioned for patients with B-cell acute lymphoblastic leukemia. Dr. Grupp also carries the distinguished title of the Yetta Deitch Novotny Endowed Chair in Pediatric Oncology at CHOP.
Selection Process for AACR Academy Fellows
The nomination and election of AACR Fellows occur via a rigorous, multi-step peer review process. Each candidate's scientific accomplishments and contributions to the realm of cancer research are scrutinized thoroughly. Only those whose work profoundly influences the field are honored with a position in the AACR Academy.
The 2025 class includes 33 newly elected Fellows, bringing the total number of AACR Academy members to 375. Both Dr. Brodeur and Dr. Grupp will receive their formal induction during the upcoming AACR Annual Meeting.
Event Details
This year’s AACR Annual Meeting is set to take place from April 25 to April 30 in Chicago, where Drs. Brodeur and Grupp will be celebrated for their outstanding achievements.
About Children's Hospital of Philadelphia
Children’s Hospital of Philadelphia, established in 1855, is the first pediatric hospital in the nation, recognized as a non-profit entity committed to exemplary patient care and profound research initiatives. The hospital's pediatric research program stands among the largest nationally, consistently contributing to developments benefitting children everywhere. The institution's dedication extends to supporting health care professionals through training programs and advanced pediatric care delivered via the CHOP Care Network, which encompasses numerous primary care practices, specialty centers, and partnerships with community hospitals across Pennsylvania and New Jersey.
CHOP’s family-centered care approach and community service efforts further cement its reputation as a leading advocate for children and adolescents' health and well-being. For additional details, please visit https://www.chop.edu.
Frequently Asked Questions
Who are the researchers honored by the AACR Academy?
Garrett M. Brodeur, MD, and Stephan A. Grupp, MD, PhD, from Children's Hospital of Philadelphia are the honored researchers.
What is the significance of the AACR Academy Fellowship?
This fellowship recognizes leading scientists whose research has significantly advanced cancer treatment and understanding.
When will the AACR Annual Meeting take place?
The meeting is scheduled from April 25 to April 30.
What are Dr. Brodeur's contributions to cancer research?
Dr. Brodeur has made significant strides in neuroblastoma research, including contributions to identifying important disease markers and developing effective treatments.
What innovative treatment did Dr. Grupp help develop?
Dr. Grupp is known for his work on CAR T-cell therapy, which has revolutionized treatment for pediatric leukemia.
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