Celebrating a Decade of DNBSEQ™: Innovations and Impact

Celebrating a Decade of DNBSEQ™ Technology

MGI Tech Co., Ltd. (NASDAQ: MGI) is thrilled to celebrate ten years of its revolutionary DNBSEQ™ sequencing technology. This milestone marks a significant journey in transforming the landscape of genomics, offering solutions that not only enhance scientific research but also make genomic information more accessible to a broader audience.

DNBSEQ™, launched commercially in 2015, has quickly established itself as a cornerstone in genomic research. Over the past decade, the platform has facilitated over 3,900 installations and has contributed to more than 10,900 peer-reviewed publications*, showcasing its pivotal role in advancing precision medicine, public health initiatives, and biodiversity studies.

The Power of Innovation

At the heart of DNBSEQ™ technology is an innovative DNA nanoball (DNB) concept that utilizes patterned arrays to enhance sequencing capabilities. This method significantly boosts accuracy while minimizing duplication rates and index hopping, thus ensuring high-quality data at a fraction of traditional sequencing costs. Researchers value DNBSEQ™ for its reliability in various applications, including whole-genome sequencing (WGS) and whole-exome sequencing (WES).

The versatility of DNBSEQ™ is further underscored by its application in eukaryotic genomics, metagenomics, and microbial research. Its adaptability allows researchers to explore complex biological questions with confidence, proving its place as an essential tool in genomic exploration.

Diverse Sequencing Options

Continuing to lead the industry, MGI offers a diverse range of sequencers under the DNBSEQ™ family, such as the T, G, and E series. Notably, the DNBSEQ-T20×2 was celebrated for producing the world’s first sub-$100 human genome. The DNBSEQ-T7 continues to be a top choice for high-throughput operations, while the DNBSEQ-E25 is recognized for its compact design, ideal for fieldwork and decentralized testing. The newly developed DNBSEQ-T1+, a high-speed benchtop sequencer, epitomizes MGI's relentless pursuit of innovation, combining speed and flexibility to cater to the evolving demands of genomic research.

Broadening Scientific Horizons

DNBSEQ™ isn’t just a sequencing platform; it opens avenues for multi-omics applications. It supports a vast array of research areas, including genomics, transcriptomics, epigenomics, and spatial omics. The technology's capabilities enhance scientific inquiry into disease mechanisms and environmental interactions, providing deeper insights into complex biological systems.

This technology has been rigorously tested in various extreme environments, from the Mariana Trench to the heights of Mount Everest, affirming its reliability and adaptability no matter the conditions.

Streamlined Data Management

To further augment its capabilities, MGI complements its sequencing technologies with a range of automation tools and BIT equipment. These innovations create a seamless workflow from sample preparation to data analysis, significantly improving laboratory efficiency and accessibility for researchers of all sizes.

Future Aspirations

Looking ahead, MGI is aiming for an ambitious target: the $10 genome. Building on DNBSEQ™, they are dedicated to developing next-gen sequencing technologies that will greatly diminish costs, increase accessibility, and enhance the speed of genomic insights. Dr. Rade Drmanac, the Chief Scientific Officer at MGI, shared, "DNBSEQ™ has morphed from a pioneering innovation into a global benchmark for affordable sequencing. We are determined to further unlock the potential of genomics for researchers worldwide."

Continuing the Mission

As MGI commemorates ten years of DNBSEQ™, it also reaffirms its commitment to democratizing access to genomic science. The focus remains on providing high-quality tools that empower researchers to undertake significant discoveries that improve health outcomes and foster global connectivity.

For complete insights into DNBSEQ™ technology and MGI's offerings, please explore their website.

*Statistics as of June 30, 2024.

Frequently Asked Questions

What is DNBSEQ™ technology?

DNBSEQ™ is a sequencing technology developed by MGI Tech that utilizes innovative DNA nanoball technology, resulting in highly accurate and cost-effective genomic sequencing solutions.

How has DNBSEQ™ changed genomic research?

DNBSEQ™ has transformed genomic research by providing high-performance sequencing options that are affordable and accessible, promoting advancements in various scientific fields.

What are the applications of DNBSEQ™ technology?

DNBSEQ™ technology supports applications in genomics, transcriptomics, epigenomics, and more, enabling researchers to delve into complex biological questions effectively.

How can researchers benefit from MGI's innovations?

MGI's innovations streamline genomic workflows, improve data analysis efficiencies, and reduce barriers to accessing cutting-edge sequencing technologies.

What are MGI's future goals regarding sequencing?

MGI aspires to achieve a $10 genome, further revolutionizing genomic sequencing by enhancing its affordability and accessibility for researchers around the globe.

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