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Azitra, Inc. Unveils Key Findings on Cancer Therapy Rash Treatment

Azitra is gearing up to commence its Phase 1/2 trial for a promising dermatological treatment known as ATR04-484. This innovative candidate aims to address the challenges faced by patients dealing with EGFR inhibitor-associated rashes, a common side effect for many cancer treatments.

At the upcoming 28th Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT), Azitra, Inc. (NYSE American: AZTR) will showcase a poster that outlines the details of its clinical trial. This important presentation will be held during the ASGCT conference in New Orleans, which is a significant event bringing together key players in the gene therapy and cell therapy fields.

Event Details for ASGCT Presentation

During this highly anticipated conference event, the presentation will cover essential aspects of the clinical trial, including:

Conference Description

The American Society of Gene and Cell Therapy is a vital gathering for those involved in developing next-generation therapies. Researchers and industry professionals come together to share insights and innovate in the realm of cell and gene therapies.

Key Presentation Details

The specifics of the presentation scheduled for May 15, 2025, are as follows:

• Event: American Society of Gene and Cell Therapy
• Location: New Orleans Ernest N. Morial Convention Center
• When: May 15, 2025, 5:30 PM - 7:00 PM CT
• Title: A Novel Staphylococcus epidermidis Compound for the Topical Treatment of EGFR Inhibitor-Induced Dermal Toxicity
• Presenter: Mary Spellman, MD, Chief Medical Officer

Mary Spellman, the Chief Medical Officer at Azitra, expressed enthusiasm regarding the conference: "The Annual Meeting of ASGCT is an important conference for researchers and industry leaders focused on next-generation therapies for patients in need. We are excited to present supporting evidence for our Phase 1/2 clinical study design of ATR04-484 and anticipate beginning patient dosing soon."

A Glimpse into Azitra's Innovative Portfolio

Azitra, Inc. is a biopharmaceutical company dedicated to pushing the boundaries of dermatological treatment. The company has made ambitious strides through its lead program, ATR-12, utilizing engineered strains of S. epidermidis to tackle rare skin diseases, particularly Netherton syndrome. This syndrome presents significant challenges, especially with limited approved treatment options available.

The ATR-12 program is currently undergoing a Phase 1b clinical trial focused on adult patients suffering from this rare condition. In addition to ATR-12, Azitra's ATR-04 program is positioned to address EGFRi-associated rash. Approximately 150,000 individuals across the U.S. experience this issue, making Azitra's efforts to provide a solution incredibly meaningful.

Azitra's innovative methods stem from a unique proprietary platform for engineered proteins and topical live biotherapeutic products. This platform leverages a comprehensive microbial library composed of around 1,500 bacterial strains. By integrating artificial intelligence and machine learning technologies, Azitra effectively analyzes and optimizes drug-like molecules from their extensive library.

Understanding the Need for Advanced Skin Therapies

The skin is not only the body’s largest organ but it is often the first to react to systemic treatments like chemotherapy or immunotherapy. Rashes associated with these treatments can be both uncomfortable and debilitating for patients, impacting their quality of life. This widespread effect emphasizes the necessity for effective, targeted therapies.

Azitra's commitment to offering solutions to these pressing dermatological issues reflects its broader mission to enhance patient well-being through scientifically advanced treatments. As the company advances its studies and clinical trials, the anticipation for successful outcomes grows, resonating with healthcare professionals and patients alike.

Frequently Asked Questions

What is the purpose of the ASGCT presentation by Azitra?

The presentation aims to outline the clinical trial for ATR04-484, focusing on its effectiveness in treating EGFR inhibitor-associated rash.

Who is the presenter at the event?

Mary Spellman, MD, Chief Medical Officer at Azitra, will be presenting the findings.

What does Azitra specialize in?

Azitra specializes in developing precision dermatology therapies to address various skin conditions, including Netherton syndrome and EGFRi-associated rash.

When is the Phase 1/2 trial anticipated to start?

Azitra plans to initiate dosing the first patient for the Phase 1/2 trial in the upcoming months.

Why are engineered strains of S. epidermidis important?

These engineered strains are critical for developing effective treatments for chronic skin diseases, offering innovative solutions where none are available.

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