Ardelyx Showcases XPHOZAH Data on Chronic Kidney Disease Treatment
Ardelyx to Present New Data on XPHOZAH at ASN Kidney Week
Ardelyx, Inc., a leading biopharmaceutical company, is gearing up to present additional findings on XPHOZAH (tenapanor) at the American Society of Nephrology's Kidney Week. The event is set to occur soon, and Ardelyx believes the insights shared will underscore the importance of this therapy for adults facing chronic kidney disease (CKD) while on dialysis.
Understanding XPHOZAH's Role in CKD Management
XPHOZAH stands out as the first and only phosphate absorption inhibitor (PAI) approved by the U.S. Food and Drug Administration for managing elevated phosphorus levels in patients with CKD who are on dialysis. This groundbreaking treatment serves as add-on therapy for individuals not sufficiently responding to traditional phosphate binders or who cannot tolerate them. It operates differently by blocking phosphate absorption through the primary pathway, displaying a unique mechanism that offers real hope for patients struggling with hyperphosphatemia.
Exciting Presentations Scheduled at Kidney Week
Among the enlightening presentations scheduled at Kidney Week, titles of particular interest highlight how tenapanor enhances treatment options for hyperphosphatemia. A poster titled "Sustained Phosphate Reduction Assessed by P AUC With Tenapanor Is Associated With Reduced Fibroblast Growth Factor 23 in Patients With Chronic Kidney Disease and Hyperphosphatemia on Dialysis" will be presented by key researchers. They will delve deeper into the relationship between phosphate reduction and clinical outcomes in dialysis patients.
Clinical Efficacy of Tenapanor
Another key presentation titled "Tenapanor Reduces Serum Phosphate With Similar Efficacy and Tolerability Profiles When Added to Various Phosphate Binders" promises to shed light on the tolerability and effectiveness of tenapanor. The data will underscore its versatility as an add-on medication, providing practitioners with essential insights into optimizing treatment plans for patients living with CKD.
Exhibitor Spotlight: Innovative Perspectives on Treatment
Ardelyx will further seize this opportunity by featuring an Exhibitor Spotlight session. With the title "A Different Perspective on Hyperphosphatemia Management: Evaluating Current Strategies," leading expert Dr. Steven Fishbane will provide a comprehensive review of XPHOZAH's mechanism of action, safety data, and its proven efficacy. This discussion aims to elevate understanding and application of effective strategies in managing CKD.
The Significance of Addressing Hyperphosphatemia
Hyperphosphatemia is recognized as a widespread complication in over half a million patients in the United States who grapple with CKD on dialysis. As kidney function deteriorates, patients struggle to expel excess phosphate from their bodies, often leading to dangerously elevated levels. The associated risks can drive a host of adverse health effects, making effective management crucial. Ardelyx, with its innovative XPHOZAH, offers a fresh solution in a landscape where traditional methods may fall short.
Key Safety Information on XPHOZAH
As with any medication, understanding the safety profile of XPHOZAH is paramount for healthcare providers. It is contraindicated in pediatric patients under six and those with mechanical gastrointestinal obstruction. While most adverse reactions have been mild-to-moderate, patients should be warned that severe diarrhea has been noted, demonstrating the need for careful monitoring.
About Ardelyx and Future Prospects
Founded on the mission to address unmet medical needs, Ardelyx continues to innovate in the biopharmaceutical space. With two commercial products already available in the United States, including IBSRELA (tenapanor) and XPHOZAH, Ardelyx looks toward an optimistic future. Ongoing collaborations, including international agreements, position the company for wider impacts in the treatment of conditions like hyperphosphatemia.
Frequently Asked Questions
What is XPHOZAH used for?
XPHOZAH is used to reduce serum phosphorus in adults with chronic kidney disease who are on dialysis as an adjunct therapy when traditional phosphate binders are inadequate.
When and where will Ardelyx present their findings?
Ardelyx will present their findings at the American Society of Nephrology's Kidney Week, occurring soon, with several engaging posters and discussions scheduled.
What makes XPHOZAH unique?
XPHOZAH is the first and only phosphate absorption inhibitor, offering a new mechanism of action by blocking phosphate absorption in the gut rather than through systemic treatments.
Who can take XPHOZAH?
XPHOZAH is approved for adults with chronic kidney disease on dialysis who do not respond to or cannot tolerate phosphate binders.
How does Ardelyx contribute to kidney disease treatments?
Ardelyx focuses on discovering and developing innovative treatments that effectively address significant unmet needs in conditions like chronic kidney disease, helping patients achieve better health outcomes.
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