ALX Oncology's Evorpacept and Zanidatamab Show Promising Results in Breast Cancer Trials
Significant Advances in Cancer Treatment with ALX Oncology
ALX Oncology Holdings Inc. (Nasdaq: ALXO) is at the forefront of enhancing cancer therapies by leveraging the body's immune response. The innovative work they are doing focuses on novel combinations of therapies to combat challenging forms of cancer. Recently, the company announced critical findings from a Phase 1b/2 trial that investigates the impact of two specific drugs—evorpacept and zanidatamab—on HER2-positive and HER2-low metastatic breast cancer.
Impressive Trial Results Presented at SABCS
These findings were accepted for a presentation at the prestigious San Antonio Breast Cancer Symposium (SABCS) scheduled for December 2024. This event draws attention from healthcare professionals globally, providing a platform to showcase groundbreaking research. The spotlight presentation is anticipated to generate interest in the oncological community due to the promising results of this innovative treatment combination.
Trial Overview and Objectives
The Phase 1b/2 trial is an open-label, multicenter study, allowing researchers to analyze the efficacy of evorpacept and zanidatamab together. This study offers a more profound understanding of how these therapies might work synergistically to tackle HER2-expressing cancers. Researchers aim to provide patients with more effective treatment options that could lead to better outcomes.
Details of the Presentation
During the SABCS, the presentation will detail the findings, including:
- Title: Zanidatamab in combination with evorpacept in HER2-positive and HER2-low metastatic breast cancer: Results from a phase 1b/2 study
- Abstract Number: SESS-2007
- Presenter: Dr. Alberto J. Montero, a recognized leader in breast cancer research, will share insights from this compelling study.
- When: Thursday, Dec. 12, from 7:00 a.m. to 8:30 a.m. CST
- Where: Henry B. Gonzalez Convention Center
ALX Oncology's Commitment to Innovation
ALX Oncology is dedicated to the advancement of therapies that not only target cancer cells but also enhance the immune system's capacity to fight cancer. The lead candidate, evorpacept, has shown significant potential, marking its place as a cornerstone in future immuno-oncology treatments. ALX's commitment to exploring multiple clinical trials across various cancer indications showcases their belief in personalized medicine.
Future Directions
As ALX Oncology presents its findings at the upcoming symposium, the hope remains high for translating these promising results into real-world treatments. The ongoing evaluations of evorpacept in combination with other therapies could pave the way for breakthrough therapies that enhance patient care.
Frequently Asked Questions
What is ALX Oncology focusing on with evorpacept?
ALX Oncology is advancing therapies that boost the immune system to treat cancer, particularly through the development of evorpacept.
Where will the trial results be presented?
The trial results will be presented at the San Antonio Breast Cancer Symposium in December 2024.
Who is leading the presentation of the trial results?
Dr. Alberto J. Montero will present the findings, highlighting the innovation behind the trial.
What is the goal of combining evorpacept and zanidatamab?
The combination aims to enhance treatment efficacy for patients with HER2-positive and HER2-low metastatic breast cancer.
How can I learn more about ALX Oncology?
Additional information can be found on ALX Oncology's website and their LinkedIn page, where ongoing updates about their research and development are shared.
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