Altimmune to Showcase Pemvidutide Data at The Liver Meeting 2024

Altimmune’s Upcoming Data Presentation at The Liver Meeting 2024

Altimmune, Inc. (Nasdaq: ALT) is all set to present fresh findings on the lipidomic profiles of subjects treated with pemvidutide at The Liver Meeting 2024, which will take place in San Diego. This significant event, hosted by the American Association for the Study of Liver Diseases (AASLD), is happening in mid-November. The new data aims to highlight the promising reductions of multiple classes of atherogenic and cardio-inflammatory lipids among subjects who received pemvidutide as part of a clinical trial for metabolic dysfunction-associated steatotic liver disease (MASLD).

A Glimpse into the Research Background

In a groundbreaking Phase 1b randomized, placebo-controlled study, Altimmune collected data that sets the stage for further exploration of pemvidutide's effectiveness. MASLD, often a precursor to the more severe metabolic dysfunction-associated steatohepatitis (MASH), has become an essential focus for clinicians and researchers alike. The findings from this study underscore the potential of pemvidutide to make a real difference in addressing the underlying conditions contributing to liver disease.

Details of the Presentation

In the poster presentation titled “Effect of Pemvidutide, a GLP-1/Glucagon Dual Receptor Agonist, on Plasma Lipidomic Profiles in Subjects with Metabolic Dysfunction-Associated Steatotic Liver Disease,” Dr. Sarah K. Browne, Vice President of Clinical Development at Altimmune, will reveal critical insights. According to the schedule, this presentation is set for November 15 at 1:00 PM PST, and attendees can look forward to a deep dive into the data that could influence future treatment pathways for patients suffering from MASLD.

Pemvidutide: A Promising Candidate

Pemvidutide, recognized for its innovative dual action, operates as a GLP-1/glucagon receptor agonist. This peptide-based approach is designed to tackle both obesity and MASH. The dual-receptor activation imitates how diet and exercise work together to promote weight loss: while GLP-1 helps in reducing appetite, glucagon's role increases energy expenditure. This dual effect not only shows promise in lowering body weight but also potentially enhances metabolic profiles by significantly reducing liver fat and serum lipid levels.

Clinical Advances with Pemvidutide

Throughout its clinical trials, pemvidutide has consistently demonstrated robust results, including significant weight loss and favorable outcomes on triglycerides and LDL cholesterol. Recently, it received Fast Track designation from the U.S. FDA, reflecting its importance in combating MASH. Furthermore, Altimmune is currently advancing into a Phase 2b efficacy trial with the expectation of topline data in the near future, reflecting an ongoing commitment to exploring and validating pemvidutide's benefits.

About Altimmune and Its Vision

Altimmune is a clinical-stage biopharmaceutical entity dedicated to pioneering peptide-based therapeutics. This mission extends to its innovation in developing pemvidutide, which holds the potential to address pressing health issues like obesity and MASH. The company’s strategic focus on next-generation medications indicates a solid commitment to advancing healthcare solutions that resonate with the needs of patients.

For those interested in keeping up with Altimmune’s progress and innovations, details regarding their presentations and findings are readily available on their website. Staying informed can provide insights into how future treatments may evolve within the biopharmaceutical sector.

Frequently Asked Questions

What is the significance of the data Altimmune will present?

The new data illustrates pemvidutide's potential in reducing harmful lipids linked to liver disease, which could inform better treatment strategies.

Who is presenting at The Liver Meeting 2024?

Dr. Sarah K. Browne, Vice President of Clinical Development, will present the crucial findings at the event.

When is the presentation scheduled?

The presentation is scheduled for November 15, 2024, at 1:00 PM PST.

What conditions does pemvidutide aim to treat?

Pemvidutide is developed to treat obesity and metabolic dysfunction-associated steatotic liver disease (MASLD).

How can the public access the presentation material?

The poster will be available on Altimmune's website in the Events section at the time of the presentation.

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