Akari Therapeutics Welcomes Dr. Sara Hurvitz to Advisory Board

Akari Therapeutics Strengthens Its Scientific Leadership

Akari Therapeutics, Plc (Nasdaq: AKTX), an innovative company in the oncology biotechnology field, has recently announced the formation of its Scientific Advisory Board (SAB). This pivotal development signifies the company's commitment to advancing its clinical and scientific strategies. The board's inaugural member is the esteemed Dr. Sara Hurvitz, a distinguished medical oncologist recognized for her significant contributions to cancer treatment.

Introducing Dr. Sara Hurvitz

Abizer Gaslightwala, CEO of Akari Therapeutics, expressed enthusiasm over Dr. Hurvitz's appointment, highlighting her extensive knowledge regarding antibody drug conjugates (ADCs). Her expertise particularly shines in managing various cancer stages, focusing on groundbreaking treatments for breast cancers, including HER2-positive and triple-negative types. Dr. Hurvitz's deep understanding of treatment paradigms will be crucial as Akari pushes forward to meet high unmet needs within oncology.

A Passion for Innovative Cancer Treatments

In her own words, Dr. Hurvitz conveyed her excitement about joining the SAB and her eagerness to contribute to developing targeted treatment options for cancer patients. She recognizes a significant opportunity to enhance scientific advancements, aiming for improved patient outcomes in fields with limited therapeutic options. Dr. Hurvitz has witnessed the profound effect of ADCs on breast cancer therapies, noting the transformative potential of targeted delivery systems. She expressed optimism regarding Akari’s preclinical results and looks forward to guiding the company's future scientific endeavors.

Dr. Hurvitz's Esteemed Career in Oncology

Dr. Hurvitz is well-respected in the oncology community, having pioneered numerous global clinical trials that have strategically influenced breast cancer treatment standards. Presently, she is a Professor of Medicine and head of the Hematology/Oncology Division at the University of Washington School of Medicine. She also leads the Clinical Research Division at Fred Hutchinson Cancer Center. Previously, Dr. Hurvitz directed the breast oncology program at UCLA, contributing significantly to the clinical research unit at Jonsson Comprehensive Cancer Center.

Acknowledgements and Impactful Contributions

Throughout her illustrious career, Dr. Hurvitz has received numerous accolades for her contributions, including the Marni Levine Memorial Breast Cancer Research Award and the European Society of Medical Oncology Breast Cancer Award. As an active practitioner, she specializes in breast cancer treatment while simultaneously leading national and international clinical trials aimed at testing innovative targeted therapies.

Akari Therapeutics' Continued Expansion

Akari Therapeutics is dedicated to expanding its ADC pipeline, which includes its leading candidate, AKTX-101, targeting the Trop2 receptor on cancer cells. This candidate operates using a proprietary linker infused with a novel PH1 payload designed to disrupt RNA splicing in cancer cells. Distinguishing itself from traditional ADCs reliant on DNA-damaging agents, AKTX-101 displays promising results in preclinical studies. These studies indicate significant tumor activity and enhanced survival rates, both as a sole agent and in conjunction with checkpoint inhibitors. Akari is committed to advancing this lead asset and exploring other undisclosed targets incorporating this innovative payload.

About Akari Therapeutics

Akari Therapeutics focuses on developing next-generation spliceosome payload antibody drug conjugates. Utilizing its advanced ADC discovery platform, the company generates candidates tailored for various targets. The novel PH1 payload has exhibited the capability to induce cancer cell death effectively while activating immune responses, promising robust clinical outcomes. This innovative approach signifies a leap forward in the realm of cancer therapeutics, exemplifying Akari’s commitment to addressing significant unmet medical needs.

Frequently Asked Questions

What is the role of the Scientific Advisory Board at Akari Therapeutics?

The Scientific Advisory Board is integral to advancing Akari's clinical and scientific strategies, providing expertise and guidance in oncology.

Who is Dr. Sara Hurvitz?

Dr. Sara Hurvitz is a renowned medical oncologist specializing in cancer treatment, known for her extensive work with antibody drug conjugates.

What is AKTX-101?

AKTX-101 is Akari Therapeutics' lead candidate targeting the Trop2 receptor, utilizing a novel payload to disrupt RNA splicing in cancer cells.

How does PH1 differ from traditional ADC payloads?

Unlike traditional ADCs that use DNA-damaging agents, PH1 as a spliceosome modulator aims to induce cancer cell death through different mechanisms.

Where can I find more information about Akari Therapeutics?

For detailed insights and updates, you can visit Akari Therapeutics’ official website.

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