Agenus Raises $22 Million Mortgage for Strategic Growth Plans

Agenus Secures a Significant Financial Boost

Agenus Inc. is thrilled to announce a successful funding achievement, securing a $22 million non-amortizing mortgage. This financial support is backed by the company's Biologics CMC facility and a sizable property, both located in California. Facilitated by skilled partners, this mortgage not only enhances Agenus' liquidity but also sets the stage for ambitious growth initiatives in the near future, ensuring they continue to push the boundaries of innovation in immuno-oncology.

A Focused Operational Realignment Strategy

In conjunction with the secured funds, Agenus is embarking on a pivotal Strategic Operational Realignment Plan. This initiative aims to hone in on the development of botensilimab/balstilimab (BOT/BAL) specifically targeting MSS colorectal cancer (CRC). The plan is meticulously designed to streamline operations and implement substantial cost-cutting measures that will propel Agenus towards a more sustainable operational model.

Cost Reduction Initiatives

The re-alignment plan encompasses a series of transformative actions. Notably, there's a projected 60% reduction in annual external expenditures. This significant cut is geared towards optimizing resource allocation and ensuring that every dollar spent contributes directly to the company’s mission.

Transitioning Capabilities

Additionally, Agenus plans to transition its current CMC capabilities to operate as a fee-for-service biologics manufacturing entity. Such a strategic move not only enhances operational efficiency but also opens additional revenue streams, setting Agenus up for long-term success.

Advancements in Clinical Research

With robust clinical data indicating exceptional activity from BOT/BAL in treating MSS CRC and various other challenging cancers, Agenus stands ready to advance its development and regulatory strategies. The objective is to attain both regional and global registration to ensure that these critical therapies reach the patients who need them most.

A Commitment to Cancer Innovation

Agenus' commitment to revolutionizing cancer treatment is underscored by the promising clinical data highlighting the transformative potential of BOT/BAL. This innovation is crucial for patients facing limited options in their treatment journeys. With financial and operational strategies in place, the company is prepared to make a meaningful impact on patient lives.

About Agenus

Agenus is a frontrunner in the field of immuno-oncology, with a rich history stemming back to its founding in 1994. The company's mission centers around expanding the benefits of cancer immunotherapy to broader patient populations. Utilizing a diverse range of therapeutic approaches, including antibody-based solutions and cell therapies, Agenus is committed to pioneering cancer care through comprehensive research, discovery, and manufacturing capabilities. Headquartered in Lexington, MA, Agenus is poised for an exciting future.

About L&L Capital

L&L Capital stands as a dedicated partner in the realm of property financing. Specializing in real estate lending, they provide customized bridge financing solutions to companies looking to leverage their real estate assets effectively. Their expertise in navigating complex financial landscapes ensures that partner companies can thrive.

About Botensilimab (BOT)

Botensilimab (BOT) is distinguished as a human Fc enhanced CTLA-4 blocking antibody. Its innovative design aims to bolster both innate and adaptive immune responses against tumors, especially those that tend to resist current treatment protocols. With an extensive clinical trial history highlighting positive outcomes, botensilimab serves as a beacon of hope across varied cancer types.

Frequently Asked Questions

What is the purpose of the $22 million mortgage secured by Agenus?

The mortgage aims to enhance Agenus' cash position and support strategic initiatives for growth and innovation.

How will the funds be utilized within the company?

The funds will primarily support the development of botensilimab/balstilimab for MSS colorectal cancer while facilitating a reduction in operational costs.

What is the Strategic Operational Realignment Plan?

This plan focuses on optimizing resources, reducing expenditures, and transitioning CMC capabilities to a fee-for-service model.

What are the clinical activities related to BOT/BAL?

BOT/BAL has shown significant clinical activity in treating MSS CRC and several other cancers, with ongoing late-stage development plans.

Why is Agenus focused on cancer immunotherapy?

Agenus aims to broaden patient access to effective cancer treatments through its innovative immuno-oncology therapies and research initiatives.

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