Addgene Launches New Service to Enhance Viral Vector Research

Addgene Unveils Enhanced Viral Vector Service

Addgene, a dedicated organization focused on streamlining the research process for scientists, has made a significant announcement. The company is expanding its viral vector service with an innovative feature known as Packaged on Request. This new service allows researchers to choose from a diverse range of AAV plasmids available in Addgene's extensive catalog and request their preferred serotype for viral vector packaging. This comes with the rigorous quality control standards that Addgene is known for, ensuring that researchers receive the highest quality preparations for their work.

Expanding Research Flexibility

In the competitive field of scientific research, having access to high-quality materials is crucial. Addgene's introduction of the Packaged on Request option is aimed squarely at providing scientists with greater flexibility in their work. Researchers can now order tailored viral vectors, making it easier to obtain precisely what they need. Melina Fan, Ph.D., Co-Founder and Chief Scientific Officer at Addgene, emphasizes this important development by stating, "Our new Packaged on Request offering serves as a tremendous leap forward in the pursuit of our mission to reduce barriers to accessing high-quality research materials."

Comprehensive Service for Researchers

The Packaged on Request service is comprehensive, enabling customers to select research-grade viral vector preparations from an impressive catalog of over 3,000 AAV plasmids. During the initial phase of the service, five distinct serotypes will be available: AAV1, AAV2, AAV5, AAV8, and AAV Retrograde capsids. This variety greatly enhances the option available to researchers, catering to diverse experimental requirements.

Maintaining Quality Standards

Maintaining unparalleled quality standards is at the heart of Addgene’s operations. Each order through the Packaged on Request service will undergo a battery of quality assurance tests. These include ddPCR titering, purity testing, sterility testing, and even viral genome sequencing, crucial steps that uphold Addgene’s commitment to delivering only the best to its users. Typical titers for the plasmids packaged into AAV1, AAV5, AAV8, and AAV Retrograde capsids will reach high levels of 1x10¹³ GC/mL, while AAV2 will perform at an impressive 7x10¹² GC/mL, consistently matching Addgene’s in-stock standard preparations.

Streamlining Administrative Processes

A unique advantage of the Packaged on Request service is its seamless integration within Addgene's existing ordering system. Researchers at academic and nonprofit institutions can effortlessly select and request AAV packaging straight from the material pages in Addgene's catalog. With this streamlined approach, Addgene also manages the necessary tech transfer terms and legal approvals, simplifying the administrative side of the experimental process and allowing scientists to focus more on their research.

Commitment to Research Excellence

As the landscape of scientific research evolves, Addgene remains committed to facilitating progress through excellence in viral vector production. Chonnettia Jones, Ph.D., President and Executive Director at Addgene, reinforces this commitment by stating, "While Packaged on Request provides researchers with increased choices, we apply our hallmark quality controls, customer support, and legal approvals to all orders." This dedication serves to strengthen partnerships with scientists globally, ensuring that Addgene not only meets but exceeds their expectations in viral vector research.

Conclusion and What Lies Ahead

In conclusion, Addgene’s Packaged on Request service heralds a new era of flexibility and quality in the preparation of viral vectors. This development puts a powerful tool into the hands of researchers, fostering an environment where innovation can thrive. For more detailed information about this exciting new offering, researchers are encouraged to visit Addgene's website—or explore their vast catalog to discover the vast possibilities enabled by this service.

Frequently Asked Questions

What is the Packaged on Request service by Addgene?

The Packaged on Request service allows researchers to request viral vector packaging from a selection of AAV plasmids in their preferred serotype, ensuring high standards of quality control.

Which serotypes are available under this service?

Addgene currently offers five serotypes: AAV1, AAV2, AAV5, AAV8, and AAV Retrograde capsids.

How does Addgene ensure the quality of its products?

Each order undergoes thorough testing, including ddPCR titering, purity, sterility tests, and viral genome sequencing to meet Addgene's high-quality standards.

Who can access the Packaged on Request service?

This service is available to scientists working in academic and nonprofit institutions through Addgene's catalog.

What advantages does this service offer researchers?

The service enhances flexibility, simplifies the ordering process, and provides tailored viral vectors to meet specific research needs, all while maintaining quality control.

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