Achieve Innovations in Nicotine Treatment at Upcoming Conference

Achieve Life Sciences Set to Highlight Cytisinicline at Conference

Achieve Life Sciences, Inc. (NASDAQ: ACHV), a prominent late-stage specialty pharmaceutical company, is gearing up to showcase its advancements in addressing nicotine dependence through its innovative drug, cytisinicline. This pivotal moment will take place during the BTIG Virtual Biotechnology Conference, a significant platform for insight into the biotechnology sector, being held from July 29-30, 2025.

Innovative Approach to Smoking Cessation

At the forefront of Achieve's agenda at the conference is the participation of Rick Stewart, the Chief Executive Officer. He is anticipated to engage in a fireside chat with Julian Harrison, a distinguished biotechnology analyst from BTIG. This session will take place on Tuesday, July 29, at 3:20 pm EDT and will delve into the comprehensive development and commercialization strategies surrounding cytisinicline.

Understanding Cytisinicline's Role

Cytisinicline is a plant-derived alkaloid specifically developed to combat nicotine addiction. While approximately 29 million adults in the United States still engage in smoking, cytisinicline aims to change the landscape of nicotine dependence by offering a scientifically backed alternative for smoking cessation. Current tobacco use is the leading cause of preventable death globally, responsible for millions of fatalities each year. The development of effective cessation treatments like cytisinicline is more crucial than ever.

Recent Developments and Clinical Trials

The progress Achieve Life Sciences has made towards its New Drug Application (NDA) submission to the FDA marks a significant milestone. The application, submitted in June 2025, is based on robust data from successfully completed Phase 3 studies and an extensive open-label safety study. Furthermore, Achieve is not just focusing on traditional smoking cessation; it has recently concluded a Phase 2 study investigating the use of cytisinicline for vaping cessation, indicating its versatility as a treatment for different forms of nicotine addiction.

Current Landscape of Nicotine Use

As e-cigarette usage surges among adults and youth—approximately 17 million adults currently use e-cigarettes—Achieve's cytisinicline has been granted Breakthrough Therapy designation by the FDA. This endorsement underscores the urgent need for more effective treatment options, particularly as current offerings for nicotine e-cigarette cessation are limited.

The Mechanism of Action

Cytisinicline operates by interacting with nicotinic receptors in the brain, reducing both the craving and the rewarding effects associated with nicotine. The aim is to alleviate symptoms of nicotine withdrawal while minimizing the satisfaction derived from continued smoking or vaping. As this investigational product candidate progresses, it is clear that cytisinicline holds potential for both smokers and vapers alike.

Achieve Life Sciences: A Mission to Improve Public Health

Achieve Life Sciences is steadfast in its commitment to fighting the nicotine dependence epidemic. With growing awareness and acknowledgment of the health hazards linked to tobacco use, Achieve is taking significant steps toward changing lives. Its focus on developing cytisinicline as an evidence-based treatment for nicotine dependence is a crucial component in the battle against smoking and its associated health risks.

Future Directions

Looking ahead, Achieve Life Sciences is poised to play a vital role in the evolution of nicotine treatment. By embracing scientific innovation and clinical advances, the company not only aims to expand the therapeutic options for nicotine dependence but also strives to enhance the quality of life for many individuals seeking to break free from cigarettes and e-cigarettes. As the conference approaches, stakeholders and investors will undoubtedly watch closely to see how Achieve continues to navigate its path in this pivotal industry.

Frequently Asked Questions

What is Achieve Life Sciences focused on?

Achieve Life Sciences focuses on developing cytisinicline as a treatment for nicotine dependence and smoking cessation.

When will Achieve Life Sciences participate in the conference?

The company will participate in the BTIG Virtual Biotechnology Conference on July 29-30, 2025.

Who will represent Achieve Life Sciences at the conference?

Rick Stewart, the CEO, will participate in a fireside chat during the conference.

What is cytisinicline?

Cytisinicline is a plant-based alkaloid aimed at helping individuals overcome nicotine addiction.

What recent progress has Achieve Life Sciences made?

Achieve Life Sciences recently submitted a New Drug Application to the FDA for cytisinicline in June 2025.

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