Acadia Pharmaceuticals Teams Up with Saniona for SAN711 Project
Acadia Pharmaceuticals Enters Exclusive License Agreement
Acadia Pharmaceuticals Inc. (NASDAQ: ACAD) has just revealed an exciting exclusive license agreement with Saniona for SAN711, a groundbreaking GABAA-?3 positive allosteric modulator. This landmark agreement promises to boost the company’s pipeline of innovative therapies. The drug is set to address essential tremor, a neurological disorder characterized by involuntary shaking. Acadia has ambitious plans, eyeing a Phase 2 clinical trial for SAN711 focused on this condition.
Understanding SAN711 and Its Potential
SAN711 stands out as a first-in-class treatment that works on the GABA receptor system in the brain to help manage essential tremor symptoms effectively. This neurological condition has long required fresh therapeutic approaches, and SAN711 aims to fill that void. The initial focus will be on its application for essential tremor, which can significantly impair daily living.
Quote from Leadership
"Licensing SAN711 to expand our pipeline underscores our unwavering commitment to delivering innovative therapies for patients with central nervous system disorders," expressed Catherine Owen Adams, Chief Executive Officer. She emphasized that essential tremor treatment has remained stagnant, leading to an urgent need for new solutions. Acadia's expertise in neurology will drive the development of SAN711 and potentially revolutionize treatment options for this condition.
Financial Details of the Agreement
The exclusive license agreement is structured to ensure that Saniona receives an upfront payment of $28 million. They may also benefit from milestone payments that could reach as high as $582 million, demonstrating Acadia's confidence in the drug’s future. The royalty structure includes tiered rates ranging from mid-single digits to low double digits on net sales, reflecting the expected market performance of SAN711. Potential milestone payments are tied to key developmental and commercial goals, which signify both companies' shared commitment to the drug's success.
Clinical Development and Support
Acadia will lead the clinical trials and regulatory processes for SAN711 while also supporting Saniona’s ongoing Phase 1 study and preparations for the subsequent Phase 2. This collaborative effort is indicative of the company's strategy to expand its portfolio with valuable assets that complement its existing product lineup.
About Acadia Pharmaceuticals
Acadia Pharmaceuticals is at the forefront of psychiatric and neurological innovation, committed to elevating the quality of life for patients facing challenging conditions. The company has made significant strides in advancing treatments for disorders such as Parkinson's disease-related psychosis and Rett syndrome, both of which saw their first FDA-approved therapies developed by Acadia. In addition to SAN711, their clinical pipeline extends to various other neurological and neuropsychiatric disorders, showcasing their dedication to addressing important unmet medical needs.
Frequently Asked Questions
What is the main goal of the license agreement between Acadia and Saniona?
The agreement aims to develop and commercialize SAN711 for essential tremor, a significant neurological condition.
How much will Saniona receive as part of the agreement?
Saniona will get an upfront payment of $28 million and potential milestone payments up to $582 million based on development achievements.
What are the expected benefits of SAN711?
SAN711 is designed to manage symptoms of essential tremor effectively, offering a much-needed treatment option for patients.
When does Acadia plan to start clinical trials for SAN711?
Acadia is planning to initiate a Phase 2 study of SAN711 in the near future, aiming for swift progression through clinical phases.
What other conditions does Acadia Pharmaceuticals focus on?
Acadia has a diverse portfolio targeting conditions like Alzheimer's disease psychosis, Prader-Willi syndrome, and various neuropsychiatric symptoms.
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