Soligenix to Showcase HyBryte™ Study Results at EORTC Conference

Soligenix to Showcase HyBryte™ Study Results at EORTC Conference

Soligenix, Inc. (Nasdaq: SNGX), a biopharmaceutical company dedicated to addressing critical medical needs in rare diseases, is set to present groundbreaking findings on the therapeutic efficacy of HyBryte™ (synthetic hypericin) for cutaneous T-cell lymphoma (CTCL) at an esteemed oncology conference.

Enhanced Response Rates with Extended Treatment

The presentation at the European Organisation for Research and Treatment of Cancer (EORTC) Annual Meeting promises to deliver insightful data from two supportive trials, showcasing how HyBryte™ therapy has enhanced response rates due to prolonged treatment durations and increased light dosing.

Highlighting Key Presentations

Dr. Ellen Kim from the University of Pennsylvania will be presenting a poster detailing expanded preliminary results from an investigator-initiated study. Meanwhile, Dr. Brian Poligone from the Rochester Skin Lymphoma Medical Group will give a presentation on the outcomes from two pivotal treatment studies. Both sessions reflect the commitment to substantial advancements in treating CTCL through innovative therapeutic approaches.

Overview of the HyBryte™ Treatment

HyBryte™ utilizes photodynamic therapy enhanced by synthetic hypericin, an effective photosensitizer for treating skin lesions. Unlike conventional therapies, this treatment engages visible light activation approximately 24 hours post-application. This method not only delivers effective outcomes but also aims to reduce risks associated with traditional DNAtargeting treatments which can lead to secondary malignancies.

Clinical Trial Insights

Research has underlined that patients utilizing HyBryte™ exhibited statistically significant improvements in lesion response rates when compared to placebo treatments. The Phase 3 clinical trials revealed a notable 16% of participants achieving substantial lesion reduction following their treatment cycles, emphasizing the potential of HyBryte™ in clinical settings.

Why EORTC Matters for Soligenix

The EORTC CLTG meeting serves as a crucial platform for specialists in the field of hematology and dermatology to converge and discuss advancements in skin lymphoma treatments. This marks an opportunity for Soligenix to solidify its role as a key player in this niche market.

Research Aimed at CTCL

CTCL represents a challenging area in oncology with no established cure. Soligenix aims to push boundaries through rigorous research and studies, which continuously showcase HyBryte™ as a potentially safer alternative that minimizes risks involved with other therapeutic approaches.

Recent Developments in Treatment Protocols

As part of ongoing efforts, Soligenix is preparing to initiate FLASH2, a confirmatory Phase 3 trial expected to embark before the year concludes. This study is intended to affirm earlier findings about the efficacy of HyBryte™ while adhering to the expectations set forth by regulatory bodies.

Addressing the Need for Innovation

The landscape of CTCL treatment continues to demand innovation, given the limited options available to patients. Soligenix is well aware of this need and is proactively working to develop HyBryte™ as a front-line therapy that not only improves patient outcomes but also adheres to safety protocols, showcasing its commitment to both efficacy and safety in treatment.

Commitment to Patient Welfare

The company’s focus on safety is paramount. With side effects historically associated with skin cancer treatments, Soligenix is dedicated to ensuring that HyBryte™ remains a safe and effective option for patients battling CTCL.

Conclusion and Future Steps

With vital presentations scheduled and further studies on the horizon, Soligenix is equipped to contribute pivotal advancements to the treatment of CTCL. As the medical community awaits upcoming research findings, there is increasing optimism for patients seeking effective and safer treatment alternatives.

Frequently Asked Questions

What is HyBryte™?

HyBryte™ is a first-in-class photodynamic therapy using synthetic hypericin for treating cutaneous T-cell lymphoma.

Where will the findings from Soligenix be presented?

The findings will be presented at the European Organisation for Research and Treatment of Cancer (EORTC) conference.

What are the expected benefits of extended treatment with HyBryte™?

Extended treatment aims to improve response rates and enhance patient outcomes while minimizing risks associated with traditional therapies.

Is there ongoing research involving HyBryte™?

Yes, Soligenix is preparing to initiate the FLASH2 study, a confirmatory Phase 3 trial to further validate HyBryte™'s efficacy.

What health issues does CTCL entail?

CTCL is a form of non-Hodgkin's lymphoma characterized by malignant T-cells and presents significant treatment challenges due to its complexity.

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