Introducing the EVOM Chip for Enhanced Research
World Precision Instruments (WPI), renowned for its expertise in transepithelial electrical resistance (TEER) technology, has teamed up with SynVivo to launch an exciting new product: the EVOM™ Chip. This innovative multiplex TEER system is a game-changer, allowing for real-time and non-destructive monitoring of organ-on-chip (OOC) platforms.
What the EVOM Chip Brings to the Table
Designed specifically to support SynVivo's leading Blood-Brain Barrier (BBB) OOC model, the EVOM™ Chip is equipped with embedded electrodes that facilitate on-chip, multiplex TEER measurements. Researchers can continuously monitor barrier integrity, paving the way for an efficient monitoring process that enhances accuracy, precision, and reproducibility without compromising cell health.
Addressing Challenges in the OOC Market
The organ-on-chip market continues to expand rapidly, yet it struggles with challenges such as standardization and automation—critical factors necessary for widespread acceptance in pharmaceutical research. Mark Rutledge, CEO of WPI, points out, "A significant gap has been the ability to perform on-chip, non-destructive sensing, especially TEER measurements—something that most OOC platforms need but seldom implement successfully in a multiplex format." The EVOM™ Chip aims to fill this gap, enabling researchers to monitor their OOC setups throughout the various phases of research, from cell seeding to drug treatment, assuring accurate and reproducible results.
Collaboration Brings Transformative Solutions
WPI has made a name for itself with its EVOM™ line, which has supported over 4,000 peer-reviewed publications in the field of barrier integrity measurement. SynVivo, a trusted partner of WPI, stands at the forefront of integrating TEER technology into both traditional and OOC frameworks. Gwen Fewell, CEO of SynVivo, expresses excitement about this collaboration, stating, "Integrating TEER measurement directly into our chip enhances data fidelity, diminishes variability, and streamlines experimental workflows. This is crucial for developing more reliable, standardized, and scalable in vitro models."
Powering Research with Standardization
The release of the EVOM™ Chip will standardize TEER measurements across SynVivo's organ-on-chip platforms, thus enabling consistent comparison of results across various experiments and laboratories. The principles that went into the EVOM™ Chip design will extend to future barrier tissue platforms, providing researchers with dependable and reproducible data vital for drug development and disease modeling.
Event Details: Experience the EVOM Chip
Attendees can explore the EVOM™ Chip at the upcoming MPS World Summit. This event will showcase the system's capabilities, allowing visitors to engage with teams to learn how to seamlessly integrate TEER technology into their research efforts. Be sure to stop by:
- WPI Booth #131
- SynVivo Booth #404
About World Precision Instruments
For over 55 years, World Precision Instruments (WPI) has remained a leader in manufacturing innovative research equipment and laboratory supplies for life sciences, pharmaceuticals, healthcare, and industrial markets. WPI's advanced technology supports the development of complex models, including preclinical models and organ-on-a-chip systems, aiding researchers in drug identification and validation processes while providing insights into pharmacokinetics and safety.
About SynVivo
SynVivo is a frontrunner in the organ-on-chip space, focused on developing physiologically relevant tissue models aimed at revolutionizing drug discovery, disease research, and safety assessments. Their microfluidic systems replicate human tissue environments, significantly boosting the accuracy of in vitro tests and contributing to more meaningful clinical outcomes.
Frequently Asked Questions
What is the EVOM Chip?
The EVOM Chip is a groundbreaking multiplex TEER system from World Precision Instruments and SynVivo designed for real-time monitoring of organ-on-chip models.
How does the EVOM Chip benefit researchers?
It allows continuous monitoring of barrier integrity with enhanced accuracy and reproducibility without affecting cell health, facilitating better research outcomes.
Where can I see the EVOM Chip in action?
The EVOM Chip will be showcased at the MPS World Summit, with opportunities to interact with team members and learn about its features.
Who are the key players behind the EVOM Chip?
The EVOM Chip was developed in collaboration between World Precision Instruments and SynVivo, leveraging their expertise in TEER technology.
What challenges does the OOC market face that the EVOM Chip addresses?
The OOC market struggles with standardization and automation; the EVOM Chip aims to fulfill the need for reliable, non-destructive sensing throughout the research process.
