Allocation : Randomized
Interventional Model : Factorial Assignment
Interventional Model Description: We will apply an integrated, mechanistically complementary combination of therapeutic interventions to obtain sustained HIV remission without antiretrovirals. These approaches will include (i) intensified antiretroviral treatment using 2 NRTIs, dolutegravir, boosted darunavir/r, and maraviroc or Leronlimab , (ii) use of the HDACi nicotinamide Riboside or nicotinamide, and dendritic cell therapy using peptides of autologous HIV.
https://clinicaltrials.gov/study/NCT07903441?...mp;rank=19