Quote:Is there a significant difference between the composition of the tumors in tnbc and CRC?
yes of course every cancer is different its well documented and JL knows that
Quote:Is there a difference between breast tissue and CR tissue?
yes of course there is its well documented and JL knows that
Quote:Is this difference helpful or not? Does it even matter?
it matters tremendously. keytruda has failed in as many cancer indications as it has excelled in
Quote:..."because of the breast cancer data, the higher dose looked much better."JL Any thoughts?
the tnbc data showed a clear difference between lower and higher dose response. 350 wasnt great. 525 and 700 were much better, particularly for PD-L1 inducement. also MASH 350 wasnt good, 700 was good. HIV monotherapy 350 wasnt good. 700 was great.